Authors: | Wang, P.; Dong, S.; Brailsford, J. A.; Iyer, K.; Townsend, S. D.; Zhang, Q.; Hendrickson, R. C.; Shieh, J.; Moore, M. A. S.; Danishefsky, S. J. |
Article Title: | At last: Erythropoietin as a single glycoform |
Abstract: | Wild thing: The first total synthesis of wild-type erythropoietin glycoprotein (see picture) has been accomplished. The erythropoietic activity of the synthetic folded protein has been demonstrated. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Keywords: | erythropoietin; glycoproteins; total synthesis; aspartylation |
Journal Title: | Angewandte Chemie - International Edition |
Volume: | 51 |
Issue: | 46 |
ISSN: | 1433-7851 |
Publisher: | Wiley Blackwell |
Date Published: | 2012-11-12 |
Start Page: | 11576 |
End Page: | 11584 |
Language: | English |
DOI: | 10.1002/anie.201206090 |
PROVIDER: | scopus |
PMCID: | PMC3500780 |
PUBMED: | 23012228 |
DOI/URL: | |
Notes: | --- - "Export Date: 3 December 2012" - "CODEN: ACIEF" - "Source: Scopus" |