Trigeminal neurosarcoidosis: Case report and literature review Journal Article


Authors: Amin, A.; Balderacchi, J. L.
Article Title: Trigeminal neurosarcoidosis: Case report and literature review
Abstract: Sarcoidosis rarely manifests by involving the cranial nerves exclusively. A 35-year-old woman presented with bilateral cavernous sinus masses and symptoms of trigeminal neuropathy. Computed tomography and magnetic resonance imaging suggested an intracranial tumor, favoring a meningioma. The patient underwent emergent surgical decompression and tumor excision. Histopathology of the resected tumor revealed classic features of sarcoidosis, and she received steroid treatment accordingly. Neurosarcoidosis must be considered in the differential diagnosis of idiopathic cranial neuropathies to avoid unnecessary surgery, since surgery has little, if any, role in the treatment of sarcoidosis. In the absence of primary organ involvement, radiologic diagnosis of cranial nerve sarcoidosis is unreliable; histopathology is required to reach a definitive diagnosis. © 2010, Vendome Group, LLC. All rights reserved.
Keywords: adult; clinical feature; disease course; histopathology; case report; nuclear magnetic resonance imaging; brain neoplasms; magnetic resonance imaging; computer assisted tomography; diagnosis, differential; tomography, x-ray computed; biopsy; decompression surgery; meningioma; sarcoidosis; cavernous sinus; trigeminal neurosarcoidosis; trigeminus neuralgia; trigeminal nerve diseases
Journal Title: Ear, Nose & Throat Journal
Volume: 89
Issue: 7
ISSN: 0145-5613
Publisher: Vendome Group Llc  
Date Published: 2010-07-01
Start Page: 320
End Page: 322
Language: English
PUBMED: 20628992
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 20 April 2011" - "CODEN: ENTJD" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Ali Amin
    3 Amin