Bone marrow metastases from glioblastoma multiforme - A case report and review of the literature Journal Article
| Authors: | Rajagopalan, V.; El Kamar, F. G.; Thayaparan, R.; Grossbard, M. L. |
| Article Title: | Bone marrow metastases from glioblastoma multiforme - A case report and review of the literature |
| Abstract: | Clinically detected extra-cranial metastases from glioblastoma multiforme (GBM) are quite rare, with an incidence of <2% reported in the published literature. Among the various reported sites of systemic metastases from GBM, there are few cases of clinically symptomatic bone marrow metastasis. The case of a patient developing systemic dissemination of a GBM is described. A 60-year-old man with GBM who developed back pain, thrombocytopenia and subsequently neurological deficits was found to have extensive bony and bone marrow metastases. Previously reported cases of extra-cranial systemic spread of GBM and attempts made in the literature to explain the possible routes of extra-neural dissemination are reviewed. © Springer 2005. |
| Keywords: | adult; bone neoplasms; middle aged; case report; bone metastasis; cancer radiotherapy; temozolomide; brain neoplasms; magnetic resonance imaging; anemia; thrombocytopenia; incidence; carmustine; irinotecan; backache; celecoxib; glioblastoma; medical literature; glioblastoma multiforme; symptomatology; fatal outcome; neurologic disease; low back pain; bone marrow neoplasms; rare diseases; bone metastases; bone marrow metastasis; bone marrow metastases |
| Journal Title: | Journal of Neuro-Oncology |
| Volume: | 72 |
| Issue: | 2 |
| ISSN: | 0167-594X |
| Publisher: | Springer |
| Date Published: | 2005-04-01 |
| Start Page: | 157 |
| End Page: | 161 |
| Language: | English |
| DOI: | 10.1007/s11060-004-3346-y |
| PUBMED: | 15925996 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 18" - "Export Date: 24 October 2012" - "CODEN: JNODD" - "Source: Scopus" |
