Discordance between functional magnetic resonance imaging during silent speech tasks and intraoperative speech arrest Journal Article
| Authors: | Petrovich, N.; Holodny, A. I.; Tabar, V.; Correa, D. D.; Hirsch, J.; Gutin, P. H.; Brennan, C. W. |
| Article Title: | Discordance between functional magnetic resonance imaging during silent speech tasks and intraoperative speech arrest |
| Abstract: | Object. The goal of this study was to investigate discordance between the location of speech arrest during awake cortical mapping, a common intraoperative indicator of hemispheric dominance, and silent speech functional magnetic resonance (fMR) imaging maps of frontal language function. Methods. Twenty-one cases were reviewed retrospectively. Images of silent speech fMR imaging activation were coregistered to anatomical MR images obtained for neuronavigation. These were compared with the intraoperative cortical photographs and the behavioral results of electrocorticography during awake craniotomy. An fMR imaging control study of three healthy volunteers was then conducted to characterize the differences between silent and vocalized speech fMR imaging protocols used for neurosurgical planning. Conclusions. Results of fMR imaging showed consistent and predominant activation of the inferior frontal gyrus (IFG) during silent speech tasks. During intraoperative mapping, however, 16 patients arrested in the precentral gyrus (PRG), well posterior to the fMR imaging activity. Of those 16, 14 arrested only in the PRG and not in the IFG as silent speech fMR imaging predicted. The control fMR imaging study showed that vocalized speech fMR imaging shifts the location of the fMR imaging prediction to include the motor strip and may be more appropriate for neurosurgical planning. |
| Keywords: | clinical article; controlled study; pathophysiology; nuclear magnetic resonance imaging; neurosurgery; magnetic resonance imaging; reproducibility; reproducibility of results; retrospective study; prediction; physiology; intraoperative period; cognition; craniotomy; language; frontal lobe; functional magnetic resonance imaging; hemispheric dominance; brain mapping; photography; speech disorder; task performance; speech; electrocorticography; frontal cortex; neuronavigation; peroperative complication; awake craniotomy; language mapping; speech disorders |
| Journal Title: | Journal of Neurosurgery |
| Volume: | 103 |
| Issue: | 2 |
| ISSN: | 0022-3085 |
| Publisher: | American Association of Neurological Surgeons |
| Date Published: | 2005-08-01 |
| Start Page: | 267 |
| End Page: | 274 |
| Language: | English |
| DOI: | 10.3171/jns.2005.103.2.0267 |
| PUBMED: | 16175856 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 22" - "Export Date: 24 October 2012" - "CODEN: JONSA" - "Source: Scopus" |
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