HER2 codon 655 polymorphism and breast cancer: Results from kin-cohort and case-control analyses Journal Article


Authors: Millikan, R. C.; Hummer, A. J.; Wolff, M. S.; Hishida, A.; Begg, C. B.
Article Title: HER2 codon 655 polymorphism and breast cancer: Results from kin-cohort and case-control analyses
Abstract: Several published epidemiologic studies show increased breast cancer risk for carriers of the Val-allele at codon 655 of the HER2 gene. We conducted additional analyses using data from three studies, including case-control analyses stratified on age and kin-cohort analyses using relatives of cases and controls. The results provide additional evidence that HER2 codon 655 genotype may predispose to early-onset breast cancer. © Springer 2005.
Keywords: adult; controlled study; case control study; genetics; case-control studies; clinical trial; cancer risk; allele; cancer susceptibility; proto oncogene; cohort studies; breast cancer; epidermal growth factor receptor 2; cohort analysis; genotype; risk factors; breast neoplasms; risk factor; risk assessment; breast tumor; codon; genetic predisposition; genes, erbb-2; polymorphism, genetic; meta analysis; genetic polymorphism; her2 polymorphism
Journal Title: Breast Cancer Research and Treatment
Volume: 89
Issue: 3
ISSN: 0167-6806
Publisher: Springer  
Date Published: 2005-02-01
Start Page: 309
End Page: 312
Language: English
DOI: 10.1007/s10549-004-2171-5
PUBMED: 15754131
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 10" - "Export Date: 24 October 2012" - "CODEN: BCTRD" - "Source: Scopus"
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  1. Amanda J Hummer
    60 Hummer
  2. Colin B Begg
    306 Begg