Authors: | Millikan, R. C.; Hummer, A. J.; Wolff, M. S.; Hishida, A.; Begg, C. B. |
Article Title: | HER2 codon 655 polymorphism and breast cancer: Results from kin-cohort and case-control analyses |
Abstract: | Several published epidemiologic studies show increased breast cancer risk for carriers of the Val-allele at codon 655 of the HER2 gene. We conducted additional analyses using data from three studies, including case-control analyses stratified on age and kin-cohort analyses using relatives of cases and controls. The results provide additional evidence that HER2 codon 655 genotype may predispose to early-onset breast cancer. © Springer 2005. |
Keywords: | adult; controlled study; case control study; genetics; case-control studies; clinical trial; cancer risk; allele; cancer susceptibility; proto oncogene; cohort studies; breast cancer; epidermal growth factor receptor 2; cohort analysis; genotype; risk factors; breast neoplasms; risk factor; risk assessment; breast tumor; codon; genetic predisposition; genes, erbb-2; polymorphism, genetic; meta analysis; genetic polymorphism; her2 polymorphism |
Journal Title: | Breast Cancer Research and Treatment |
Volume: | 89 |
Issue: | 3 |
ISSN: | 0167-6806 |
Publisher: | Springer |
Date Published: | 2005-02-01 |
Start Page: | 309 |
End Page: | 312 |
Language: | English |
DOI: | 10.1007/s10549-004-2171-5 |
PUBMED: | 15754131 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 10" - "Export Date: 24 October 2012" - "CODEN: BCTRD" - "Source: Scopus" |