Fine needle aspiration cytology of pleomorphic hyalinized angiectatic tumor: A case report Journal Article


Authors: Lin, O.; Crapanzano, J. P.
Article Title: Fine needle aspiration cytology of pleomorphic hyalinized angiectatic tumor: A case report
Abstract: Pleomorphic hyalinized angiectatic tumor (PHAT) of soft parts is a neoplasm characterized by spindle and pleomorphic cells associated with an angiectatic vasculature. We describe the cytological findings of a fine-needle aspiration biopsy (FNAB) from the right medial knee of a 45-yr-old woman. The aspirate material was entirely submitted in Cytolit solution. The specimen was moderately cellular and was comprised of spindle cells in a background of fibrinous material. The cells varied from small, bland spindle cells with a fine chromatin pattern and inconspicuous nucleoli to larger pleomorphic cells with coarser chromatin and occasional intranuclear inclusions. Most of the cells were arranged singly with sporadic small cluster formation with indistinct cell borders. Rare mononuclear inflammatory cells morphologically compatible with mast cells were identified. The differential diagnosis include solitary fibrous tumor (SFT) and ancient schwannoma, which also shows fibrous-like material and spindle cells that may have intranuclear inclusions. © 2005 Wiley-Liss, Inc.
Keywords: adult; bone neoplasms; middle aged; human cell; case report; cytology; cell structure; differential diagnosis; vascularization; inflammatory cell; mononuclear cell; chromatin; biopsy, fine-needle; knee; spindle cell; fibroma; aspiration biopsy; tumor; cytopathology; soft tissue tumor; reagent; cytodiagnosis; neurilemoma; mast cell; aspiration cytology; neurilemmoma; pleomorphic; histiocytoma, benign fibrous; cell nucleus inclusion body; angiectatic; hyalinized; pleomorphic hyalinized angiectatic tumor
Journal Title: Diagnostic Cytopathology
Volume: 32
Issue: 4
ISSN: 8755-1039
Publisher: Wiley Liss  
Date Published: 2005-04-01
Start Page: 238
End Page: 242
Language: English
DOI: 10.1002/dc.20219
PUBMED: 15754361
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 4" - "Export Date: 24 October 2012" - "CODEN: DICYE" - "Source: Scopus"
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  1. Oscar Lin
    307 Lin