Author: | Lima, C. D. |
Article Title: | Inducing interactions with the CTD |
Abstract: | Despite its simple repeating sequence, the C-terminal domain (CTD) of RNA polymerase II spatially and temporally recruits diverse factors to the site of transcription. A recent study reports observations consistent with an induced fit binding mechanism that is coupled to recognition of CTD proline isomerization and phosphorylation patterns. © 2005 Nature Publishing Group. |
Keywords: | protein phosphorylation; note; protein conformation; protein domain; metabolism; complex formation; serine; carboxy terminal sequence; protein protein interaction; protein binding; protein stability; genetic transcription; phosphorylation; chemistry; enzyme phosphorylation; saccharomyces cerevisiae; molecular recognition; measurement; short survey; binding site; protein structure, tertiary; saccharomyces cerevisiae proteins; saccharomyces cerevisiae protein; molecular biology; protein structure; structure analysis; rna processing; rna polymerase ii; protein tertiary structure; proline; mrna cleavage and polyadenylation factors; isomerization; binding kinetics; cleavage and polyadenylation specificity factor; cleavage factor i, s cerevisiae |
Journal Title: | Nature Structural and Molecular Biology |
Volume: | 12 |
Issue: | 2 |
ISSN: | 1545-9993 |
Publisher: | Nature Publishing Group |
Date Published: | 2005-02-01 |
Start Page: | 102 |
End Page: | 103 |
Language: | English |
DOI: | 10.1038/nsmb0205-102 |
PUBMED: | 15702066 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 6" - "Export Date: 24 October 2012" - "CODEN: NSMBC" - "Source: Scopus" |