Inducing interactions with the CTD Journal Article


Author: Lima, C. D.
Article Title: Inducing interactions with the CTD
Abstract: Despite its simple repeating sequence, the C-terminal domain (CTD) of RNA polymerase II spatially and temporally recruits diverse factors to the site of transcription. A recent study reports observations consistent with an induced fit binding mechanism that is coupled to recognition of CTD proline isomerization and phosphorylation patterns. © 2005 Nature Publishing Group.
Keywords: protein phosphorylation; note; protein conformation; protein domain; metabolism; complex formation; serine; carboxy terminal sequence; protein protein interaction; protein binding; protein stability; genetic transcription; phosphorylation; chemistry; enzyme phosphorylation; saccharomyces cerevisiae; molecular recognition; measurement; short survey; binding site; protein structure, tertiary; saccharomyces cerevisiae proteins; saccharomyces cerevisiae protein; molecular biology; protein structure; structure analysis; rna processing; rna polymerase ii; protein tertiary structure; proline; mrna cleavage and polyadenylation factors; isomerization; binding kinetics; cleavage and polyadenylation specificity factor; cleavage factor i, s cerevisiae
Journal Title: Nature Structural and Molecular Biology
Volume: 12
Issue: 2
ISSN: 1545-9993
Publisher: Nature Publishing Group  
Date Published: 2005-02-01
Start Page: 102
End Page: 103
Language: English
DOI: 10.1038/nsmb0205-102
PUBMED: 15702066
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 6" - "Export Date: 24 October 2012" - "CODEN: NSMBC" - "Source: Scopus"
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  1. Christopher D Lima
    103 Lima