The integration of chemotherapy and surgery for bladder cancer Journal Article


Authors: Galsky, M. D.; Herr, H. W.; Bajorin, D. F.
Article Title: The integration of chemotherapy and surgery for bladder cancer
Abstract: Despite surgery with curative intent, approximately 50% of patients with muscle-invasive transitional cell carcinoma of the bladder will develop distant metastases and succumb to their disease. Attempts to improve outcomes have focused on refining surgical techniques and integrating perioperative chemotherapy. This review summarizes the available literature addressing the role of pelvic lymph-adenectomy, neoadjuvant chemotherapy, and adjuvant chemotherapy in the management of patients with muscle-invasive transitional cell carcinoma of bladder. © Journal of the National Comprehensive Cancer Network.
Keywords: cancer chemotherapy; cancer survival; treatment outcome; cancer surgery; surgical technique; overall survival; clinical trial; review; cisplatin; doxorubicin; fluorouracil; antineoplastic agents; gemcitabine; paclitaxel; cancer patient; chemotherapy, adjuvant; methotrexate; antineoplastic agent; lymph node excision; lymphadenectomy; antineoplastic combined chemotherapy protocols; pelvis lymphadenectomy; cyclophosphamide; bladder cancer; cancer research; urinary bladder neoplasms; vinblastine; patient care; systematic review; adjuvant chemotherapy; cystectomy; epirubicin; neoadjuvant chemotherapy; carcinoma, transitional cell; transitional cell carcinoma; meta analysis; perioperative care
Journal Title: Journal of the National Comprehensive Cancer Network
Volume: 3
Issue: 1
ISSN: 1540-1405
Publisher: Harborside Press  
Date Published: 2005-01-01
Start Page: 45
End Page: 51
Language: English
PUBMED: 19813322
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 4" - "Export Date: 24 October 2012" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Matthew Galsky
    29 Galsky
  2. Harry W Herr
    594 Herr