Rectal cancer: Clinical practice guidelines in oncology Journal Article
| Authors: | Engstrom, P. F.; Benson, A. B. 3rd; Chen, Y. J.; Choti, M. A.; Dilawari, R. A.; Enke, C. A.; Fakih, M. G.; Fuchs, C.; Kiel, K.; Knol, J. A.; Leong, L. A.; Ludwig, K. A.; Martin, E. W. Jr; Rao, S.; Saif, M. W.; Saltz, L.; Skibber, J. M.; Venook, A. P.; Yeatman, T. J. |
| Article Title: | Rectal cancer: Clinical practice guidelines in oncology |
| Abstract: | The NCCN Rectal Cancer Guidelines panel believes that a multidisciplinary approach is necessary for treating patients with colorectal cancer. Patients with T1 or T2 lesions that are node-negative by endorectal ultrasound and who meet carefully defined criteria can be treated with a transanal excision. Abdominal peritoneal resection or low anterior resection with total mesorectal excision is appropriate for all other rectal lesions. Either preoperative chemoradiation or postoperative chemoradiotherapy is standard for patients with suspected or proven serosal invasion (pT3) or regional node involvement. Patients with recurrent localized disease should be considered for resection with or without radiotherapy. Chemotherapy regimens using irinotecan or oxaliplatin should be considered for patients with distant metastasis. The panel endorses the concept that treating patients in a clinical trial has priority over standard or accepted therapy. © Journal of the National Comprehensive Cancer Network. |
| Keywords: | cancer chemotherapy; cancer surgery; clinical feature; review; cancer recurrence; bevacizumab; fluorouracil; advanced cancer; cancer risk; dose response; multimodality cancer therapy; liver neoplasms; capecitabine; adjuvant therapy; cancer adjuvant therapy; cancer radiotherapy; radiotherapy, adjuvant; cancer staging; lymph node metastasis; antineoplastic agent; cancer diagnosis; lymphatic metastasis; neoplasm staging; clinical practice; metastasis; antineoplastic combined chemotherapy protocols; lung neoplasms; camptothecin; cancer screening; nccn clinical practice guidelines; practice guideline; oncology; cetuximab; irinotecan; standard; lung tumor; folinic acid; adjuvant chemotherapy; family history; liver tumor; medical society; drug derivative; medical oncology; colorectal surgery; neoplasm recurrence; platinum complex; oxaliplatin; drug dose regimen; rectal neoplasms; adjuvant radiotherapy; rectum cancer; rectum tumor; organoplatinum compounds; leucovorin; clinical examination; family counseling; folfox protocol; ifl protocol |
| Journal Title: | Journal of the National Comprehensive Cancer Network |
| Volume: | 3 |
| Issue: | 4 |
| ISSN: | 1540-1405 |
| Publisher: | Harborside Press |
| Date Published: | 2005-07-01 |
| Start Page: | 492 |
| End Page: | 508 |
| Language: | English |
| PROVIDER: | scopus |
| PUBMED: | 16038640 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 12" - "Export Date: 24 October 2012" - "Source: Scopus" |
