Clinical experience with local excision and postoperative radiation therapy for rectal cancer Journal Article


Author: Minsky, B. D.
Article Title: Clinical experience with local excision and postoperative radiation therapy for rectal cancer
Abstract: The standard surgical treatment for patients with potentially curable transmural and/or node-positive rectal cancer is a low anterior resection or abdominoperineal resection. There is increasing interest in the use of local excision and postoperative radiation therapy as primary therapy for selected rectal cancers. The limited data suggest that the approach of local excision and postoperative radiation therapy should be limited to patients with either T1 tumors with adverse pathologic factors or T2 tumors. Transmural tumors have a 24 percent local failure rate and are treated more effectively with standard surgery and preoperative or postoperative therapy. The results of local excision and postoperative radiation therapy are encouraging; however, more experience is needed to determine whether this approach ultimately has local control and survival rates similar to standard surgery. © 1993 American Society of Colon and Rectal Surgeons.
Keywords: cancer survival; antineoplastic agents; cancer radiotherapy; postoperative care; combined modality therapy; neoplasm staging; survival time; infant, newborn; conservative treatment; organ preservation; rectal neoplasms; rectum cancer; clinical trials; rectal cancer; local excision; conservative management; human; priority journal; article
Journal Title: Diseases of the Colon and Rectum
Volume: 36
Issue: 4
ISSN: 0012-3706
Publisher: Lippincott Williams & Wilkins  
Date Published: 1993-04-01
Start Page: 405
End Page: 409
Language: English
DOI: 10.1007/bf02053949
PUBMED: 8458271
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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  1. Bruce Minsky
    306 Minsky