Results of local excision followed by postoperative radiation therapy for rectal cancer Journal Article


Author: Minsky, B. D.
Article Title: Results of local excision followed by postoperative radiation therapy for rectal cancer
Abstract: There is increasing interest in the use of local excision and postoperative radiation therapy (RT) as a sphincter-sparing approach for selected rectal cancers. The data suggest that this treatment approach should be limited to patients with either T1 tumors with adverse pathologic factors or T2 tumors. Transmural (T3) tumors have a 25% local recurrence rate with this technique and are treated more effectively with standard surgery and pre- or postoperative therapy. The results of local excision and postoperative RT are encouraging, however, more experience is needed to determine if this approach will have similar local control and survival rates as standard surgery.
Keywords: cancer survival; excision; clinical trial; cancer recurrence; fluorouracil; cancer radiotherapy; postoperative care; chemotherapy, adjuvant; radiotherapy, adjuvant; neoplasm recurrence, local; antimetabolites, antineoplastic; radiotherapy dosage; rectal neoplasms; rectum cancer; rectal cancer; anus sphincter; sphincter preservation; conservative management; humans; human; priority journal; article
Journal Title: Radiation Oncology Investigations
Volume: 5
Issue: 5
ISSN: 1065-7541
Publisher: John Wiley & Sons  
Date Published: 1997-01-01
Start Page: 246
End Page: 251
Language: English
DOI: 10.1002/(sici)1520-6823(1997)5:5<246::aid-roi5>3.0.co;2-y
PUBMED: 9372547
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
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MSK Authors
  1. Bruce Minsky
    258 Minsky