Small molecule microarrays: From proteins to mammalian cells - Are we there yet? Journal Article
| Authors: | Chiosis, G.; Brodsky, J. L. |
| Article Title: | Small molecule microarrays: From proteins to mammalian cells - Are we there yet? |
| Abstract: | A recent publication by Stockwell and colleagues documents a leap forward toward the continued development of small molecule microarray (SMM) technology. By creating microarrays of small molecules impregnated in a biodegradable polymer, the authors have, for the first time, shown that SMMs can be used in a cell-based format. This technological improvement opens the door for using SMMs to perform high-throughput screens in mammalian cells. © 2005 Elsevier Ltd. All rights reserved. |
| Keywords: | protein array analysis; review; nonhuman; proteins; mammalia; animals; cells, cultured; protein; high throughput screening; biotechnology; medical technology; recombinant protein; dna microarray; biocompatible materials; rapamycin; polymer; mammal cell; cells; polymers; biodegradation; biodegradability; mammalian cells; small molecule transport agent; biodegradable polymers; small molecule microarrays (smm) |
| Journal Title: | Trends in Biotechnology |
| Volume: | 23 |
| Issue: | 6 |
| ISSN: | 0167-7799 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2005-06-01 |
| Start Page: | 271 |
| End Page: | 274 |
| Language: | English |
| DOI: | 10.1016/j.tibtech.2005.03.011 |
| PUBMED: | 15922078 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 9" - "Export Date: 24 October 2012" - "CODEN: TRBID" - "Source: Scopus" |
