Pathway information for systems biology Journal Article


Authors: Cary, M. P.; Bader, G. D.; Sander, C.
Article Title: Pathway information for systems biology
Abstract: Pathway information is vital for successful quantitative modeling of biological systems. The almost 170 online pathway databases vary widely in coverage and representation of biological processes, making their use extremely difficult. Future pathway information systems for querying, visualization and analysis must support standard exchange formats to successfully integrate data on a large scale. Such integrated systems will greatly facilitate the constructive cycle of computational model building and experimental verification that lies at the heart of systems biology. © 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
Keywords: signal transduction; nonhuman; animals; computational biology; models, biological; protein protein interaction; protein binding; data base; mathematical model; standard; short survey; gene control; databases, factual; information system; mathematical computing; complementary dna; gene construct; enzyme metabolism; online system; ontology; pathway data integration; pathway database; standard exchange format; bioprocess
Journal Title: FEBS Letters
Volume: 579
Issue: 8
ISSN: 0014-5793
Publisher: Wiley Blackwell  
Date Published: 2005-03-21
Start Page: 1815
End Page: 1820
Language: English
DOI: 10.1016/j.febslet.2005.02.005
PUBMED: 15763557
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 55" - "Export Date: 24 October 2012" - "CODEN: FEBLA" - "Source: Scopus"
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  1. Michael Cary
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  2. Chris Sander
    210 Sander
  3. Gary David Bader
    10 Bader