An evidence-based systematic review of echinacea ( E. angustifolia DC, E. pallida, E. purpurea) by the natural standard research collaboration Journal Article
| Authors: | Basch, E.; Ulbricht, C.; Basch, S.; Dalton, S.; Ernst, E.; Foppa, I.; Szapary, P.; Tiffany, N.; Orlando, C. W.; Vora, M. |
| Article Title: | An evidence-based systematic review of echinacea ( E. angustifolia DC, E. pallida, E. purpurea) by the natural standard research collaboration |
| Abstract: | A small clinical trial assessing the potential benefit of oral echinacea for recurrent herpes genitalis found no effect. Conclusions cannot be considered definitive without further trials. Vonau et al. conducted a randomized, placebo controlled, cross-over trial to evaluate the therapeutic use of echinacea for recurrent genital herpes. Fifty patients were randomly allocated to a treatment sequence of either echinacea extract (800 mg orally twice/day) for six months followed by placebo for six months, or vice versa. Number of recurrences and several indicators of disease status (Visual Analogue Scale of pain, CD4 counts, neutrophil counts) were assessed before and after treatments. No statistically significant differences were found between the groups. Although the sample size was relatively small, a relevant treatment benefit would likely have been detected if present. |
| Keywords: | unclassified drug; prednisone; clinical trial; drowsiness; review; hepatitis; drug efficacy; drug safety; nonhuman; skin manifestation; methotrexate; treatment indication; drug eruption; liver toxicity; leukopenia; nausea; vomiting; kidney failure; abdominal pain; drug hypersensitivity; fever; pruritus; hypotension; drug mechanism; systematic review; muscle weakness; peripheral edema; erythema; pregnancy; azathioprine; antiinflammatory activity; ascorbic acid; headache; echinacea; ketoconazole; drug dose regimen; treatment contraindication; metronidazole; anaphylaxis; heart atrium fibrillation; cyclosporin; urticaria; upper respiratory tract infection; bronchospasm; angioneurotic edema; sore throat; anabolic agent; shivering; echinacea purpurea extract; rhabdomyolysis; antimicrobial activity; amoxicillin; amiodarone; echinacea extract; kava extract; disulfiram; econazole; biracial; echinacea angustiflora extract; echinacea pallida extract; echinacin; echinaforce; echinafresh; echinaguard; esberitox; pascotox; resistan; vitamin b group; echinacea pallida; genital herpes |
| Journal Title: | Journal of Herbal Pharmacotherapy |
| Volume: | 5 |
| Issue: | 2 |
| ISSN: | 1522-8940 |
| Publisher: | Haworth Press Inc |
| Date Published: | 2005-01-01 |
| Start Page: | 57 |
| End Page: | 88 |
| Language: | English |
| DOI: | 10.1300/J157v05n02_06 |
| PROVIDER: | scopus |
| PUBMED: | 16260410 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 2" - "Export Date: 24 October 2012" - "CODEN: JHPOB" - "Source: Scopus" |
