Disseminated mycobacterium marinum infection in a hematopoietic stem cell transplant recipient Journal Article
| Authors: | Jacobs, S.; George, A.; Papanicolaou, G. A.; Lacouture, M. E.; Tan, B. H.; Jakubowski, A. A.; Kaltsas, A. |
| Article Title: | Disseminated mycobacterium marinum infection in a hematopoietic stem cell transplant recipient |
| Abstract: | Mycobacterium marinum is a photochromogenic mycobacterium that is ubiquitous in the aquatic environment. In the general population, exposure to aquaria is the most common cause of M. marinum infection. Known as "swimmer's granuloma" or "fish tank granuloma," M. marinum is an occupational hazard for aquarium cleaners and fishermen. There are several reports in the literature of M. marinum infection in immunocompromised hosts, including those with solid organ transplants, but none in patients who have received stem cell transplants (SCTs). To our knowledge, this is a first report of disseminated M. marinum infection in an SCT recipient who continued to develop new skin lesions even after months of targeted therapy. The implications are that elderly patients who receive T-cell-depleted SCTs may be at prolonged risk for pathogens dependent on cellular immunity, and the presentation of illness with such pathogens may be more severe and widely disseminated than might otherwise be expected. © 2011 John Wiley & Sons A/S. |
| Keywords: | adult; middle aged; acute granulocytic leukemia; busulfan; fludarabine; pathogenesis; case report; polymerase chain reaction; skin biopsy; skin defect; aciclovir; immunoglobulin; melphalan; hematopoietic stem cell transplantation; transplantation; fever; rash; anti-bacterial agents; cellular immunity; erythema; folic acid; multivitamin; clarithromycin; physical examination; staphylococcus infection; vancomycin; immunocompromised host; t cell depletion; doxycycline; levofloxacin; rifampicin; atovaquone; graft recipient; mycobacteriosis; thymocyte antibody; streptomycin; swelling; sulfamethoxazole; trimethoprim; pantoprazole; acute sinusitis; amoxicillin plus clavulanic acid; amikacin; skin diseases, bacterial; isoniazid; immunocompromised; mycobacterium marinum; non-tuberculous mycobacteria; mycobacterium marinum infection; mycobacterium infections, nontuberculous |
| Journal Title: | Transplant Infectious Disease |
| Volume: | 14 |
| Issue: | 4 |
| ISSN: | 1398-2273 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2012-08-01 |
| Start Page: | 410 |
| End Page: | 414 |
| Language: | English |
| DOI: | 10.1111/j.1399-3062.2011.00681.x |
| PROVIDER: | scopus |
| PUBMED: | 22093773 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 1 October 2012" - "CODEN: TIDSF" - "Source: Scopus" |
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
-
457Lacouture -
238Papanicolaou -
5Tan -
24Kaltsas -
455Jakubowski
Related MSK Work