Psychometric validation of the female sexual function index (FSFI) in cancer survivors Journal Article


Authors: Baser, R. E.; Li, Y.; Carter, J.
Article Title: Psychometric validation of the female sexual function index (FSFI) in cancer survivors
Abstract: BACKGROUND: The Female Sexual Function Index (FSFI) is the most commonly used self-report instrument to measure sexual functioning among women cancer survivors. Despite this, the validity and reliability of the FSFI for use in cancer populations has not been established. METHODS: Data were combined from 3 separate institutional review board-approved studies of the psychosexual adjustment of women cancer survivors conducted at Memorial Sloan-Kettering Cancer Center. Psychometric analysis was applied to the FSFI responses from 181 women comprising 4 cohorts, including survivors of: gynecologic cancer (all types; 2 cohorts), malignancies requiring bone-marrow/stem cell transplantation, and early stage cervical cancer. RESULTS: A factor analysis supported the subscale structure of the FSFI, yielding results nearly identical to those from the original FSFI validation study. Internal consistency reliability was 0.94 for the FSFI total score and ranged from 0.85 to 0.94 for the domain scores. Corrected item-total correlations ranged from 0.44 to 0.79 for the total score and from 0.62 to 0.88 for the domain scores. FSFI scores were correlated negatively with measures of depression, distress, and menopausal symptoms and were correlated positively with quality of life. FSFI scores exhibited a preliminary ability to discriminate between women based on whether or not they received chemotherapy and/or radiation. CONCLUSIONS: The FSFI demonstrated strong psychometric properties in this study, supporting its continued use for monitoring sexual function and cancer-related dysfunction among sexually active women who are cancer survivors. Cancer 2012. © 2012 American Cancer Society.
Keywords: adult; cancer chemotherapy; controlled study; functional assessment; major clinical study; united states; cancer radiotherapy; cancer staging; antineoplastic agent; quality of life; cohort analysis; stem cell transplantation; validation study; cancer survivor; self report; questionnaires; survivors; genital neoplasms, female; cancer center; depression; sexuality; uterine cervix cancer; scoring system; distress syndrome; malignant neoplastic disease; construct validity; reliability; bone marrow transplantation; gynecologic cancer; sexual function; chemoradiotherapy; psychometrics; internal consistency; psychometry; menopausal syndrome; clinical assessment tool; women's health; women; factorial analysis; sexual dysfunctions, psychological; female sexual function index; psychological; physiological; self-report; sexual dysfunctions
Journal Title: Cancer
Volume: 118
Issue: 18
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 2012-09-15
Start Page: 4606
End Page: 4618
Language: English
DOI: 10.1002/cncr.26739
PROVIDER: scopus
PUBMED: 22359250
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 1 October 2012" - "CODEN: CANCA" - "Source: Scopus"
Altmetric Score
MSK Authors
  1. Yuelin Li
    136 Li
  2. Raymond E Baser
    64 Baser
  3. Jeanne Carter
    107 Carter