Validation of clinical tools for vaginal and vulvar symptom assessment in cancer patients and survivors Journal Article


Authors: Eaton, A. A.; Baser, R. E.; Seidel, B.; Stabile, C.; Canty, J. P.; Goldfrank, D. J.; Carter, J.
Article Title: Validation of clinical tools for vaginal and vulvar symptom assessment in cancer patients and survivors
Abstract: Introduction Health care professionals can play a pivotal role in promoting vulvovaginal health through assessment and appropriate intervention. Aim To develop and validate brief clinical measurements to facilitate the identification of vulvovaginal symptoms in patients with and survivors of cancer. Methods One hundred seventy-five women survivors of cancer attending a Female Sexual Medicine and Women's Health Program from September 26, 2012 through October 31, 2014 completed the Vaginal Assessment Scale (VAS) and the Vulvar Assessment Scale (VuAS)—a modified version of the VAS that targets vulvar symptoms. Pelvic examination results were recorded using a clinical examination checklist. Main Outcome Measures Internal consistency of the two scales was assessed using Cronbach α, and the correlation between scales and other outcomes was reported. Results The internal consistency measurements of the VAS and VuAS at the first visit were 0.70 and 0.68, which decreased to 0.53 and 0.66 at the last visit. The VAS composite and VuAS composite scores were moderately correlated with each other (0.42 and 0.45 at first and last visits, respectively). A strong correlation was observed between VAS pain with intercourse and Female Sexual Function Index (FSFI) pain with intercourse (−0.63 and −0.71 at the first and last visits, respectively). Worse pain with examination, worse functioning on the FSFI pain, lubrication, and total scores, and worse vulvar irritation were correlated with more severe symptoms on the VAS and VuAS. Conclusion The VAS and VuAS are simple tools that can be used by clinicians to assess health concerns in women diagnosed with and treated for cancer. Validation is needed across diverse settings and groups of women. © 2016 International Society for Sexual Medicine
Keywords: adult; controlled study; aged; middle aged; major clinical study; pathophysiology; cancer patient; neoplasm; neoplasms; pain; vagina; clinical assessment; pathology; validation study; survivor; cancer survivor; survivors; questionnaire; correlation analysis; disease severity; rating scale; physical examination; sexual intercourse; sexual behavior; clinical examination; women's health; vaginal health; female sexual function index; cancer survivorship; checklist; sexual health; vulva; nose irritation; coitus; pelvic examination; vaginal lubrication; cancer; humans; human; female; priority journal; article; vulvovaginal disease; symptom assessment; vaginal assessment scale; surveys and questionnaires; vulvar health; vulvar assessment scale
Journal Title: Journal of Sexual Medicine
Volume: 14
Issue: 1
ISSN: 1743-6095
Publisher: Elsevier Inc.  
Date Published: 2017-01-01
Start Page: 144
End Page: 151
Language: English
DOI: 10.1016/j.jsxm.2016.11.317
PUBMED: 28011209
PROVIDER: scopus
PMCID: PMC5222753
DOI/URL:
Notes: Article -- Export Date: 2 January 2018 -- Source: Scopus
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MSK Authors
  1. Raymond E Baser
    133 Baser
  2. Jeanne Carter
    160 Carter
  3. Anne Austin Eaton
    122 Eaton
  4. Cara Marie Stabile
    26 Stabile
  5. Barbara A Seidel
    12 Seidel
  6. Jocelyn Patricia Canty
    6 Canty