Screening prostate cancer using a portable near infrared scanning imaging unit with an optical fiber-based rectal probe Conference Paper
| Authors: | Pu, Y.; Wang, W.; Tang, G.; Budansky, Y.; Sharonov, M.; Xu, M.; Achilefu, S.; Eastham, J. A.; Alfano, R. R. |
| Title: | Screening prostate cancer using a portable near infrared scanning imaging unit with an optical fiber-based rectal probe |
| Conference Title: | Optical Biopsy X |
| Abstract: | A portable near infrared scanning polarization imaging unit with an optical fiber-based rectal probe, namely Photonic Finger, was designed and developed o locate the 3D position of abnormal prostate site inside normal prostate tissue. An inverse algorithm, Optical Tomography using Independent Component Analysis (OPTICA) was improved particularly to unmix the signal from targets (cancerous tissue) embedded in a turbid medium (normal tissue) in the backscattering imaging geometry. Photonic Finger combined with OPTICA was tested to characterize different target(s) inside different tissue medium, including cancerous prostate tissue embedded by large piece of normal tissue. © 2012 SPIE. |
| Keywords: | three dimensional; biopsy; optical tomography; urology; probes; contrast agent; tissue; infrared devices; independent component analysis; backscattering; human prostate tissue; independent component analysis (ica); optical fiber-based rectal probe; photon propagation model; photonic finger (pf); scanning optical polarization imaging; three-dimensional localization; multiple angular view; receptor-target contrast agent; human prostate; polarization imaging; optical fibers; textile fibers |
| Journal Title | Proceedings of SPIE |
| Volume: | 8220 |
| Conference Dates: | 2012 Jan 21 |
| Conference Location: | San Francisco, CA |
| ISBN: | 0277-786X |
| Publisher: | SPIE |
| Location: | San Francisco, CA |
| Date Published: | 2012-06-01 |
| Start Page: | 822002 |
| Language: | English |
| DOI: | 10.1117/12.904254 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - Progress in Biomedical Optics and Imaging - Proceedings of SPIE - Progr. Biomed. Opt. Imaging Proc. SPIE - "Conference code: 90036" - "Export Date: 2 July 2012" - "Sponsors: The Society of Photo-Optical Instrumentation Engineers (SPIE); Hamamatsu Corporation; Ocean Optics, Inc.; Intuitive Surgical Inc.; PerkinElmer Inc." - 24 January 2012 through 25 January 2012 - "Source: Scopus" |
