Clinical and dermoscopic characteristics of amelanotic melanomas that are not of the nodular subtype Journal Article

  


Authors: Jaimes, N.; Braun, R. P.; Thomas, L.; Marghoob, A. A.
Article Title: Clinical and dermoscopic characteristics of amelanotic melanomas that are not of the nodular subtype
Abstract: Background Amelanotic melanomas remain challenging to diagnose. Objective To analyze and describe the clinical and dermoscopic characteristics of amelanotic melanomas that are not of the nodular subtype. Patients/Methods We conducted a retrospective review of 20 consecutively diagnosed amelanotic melanomas. The clinical and dermoscopic images of pathologically confirmed amelanotic melanomas that were not of the nodular subtype were analyzed. In addition, the clinical diagnosis and the reasons why these lesions were biopsied were examined. Results All 20 amelanotic melanomas were erythematous and lacked any of the clinical ABCD features commonly attributed to melanoma. The lesions appeared clinically to be relatively symmetric with regular borders and manifesting a circular to oval morphology. Dermoscopically, all lesions manifested polymorphous vascular pattern. Conclusions Amelanotic melanomas that are not of the nodular subtype often present as clinically symmetric erythematous lesions. Therefore, it is important to consider AMs in the differential diagnosis of isolated and persistent erythematous outlier lesions, even if they are symmetric in appearance. Additionally, the presence of a polymorphous vascular pattern seen with dermoscopy can facilitate in correctly identifying these melanomas. © 2011 European Academy of Dermatology and Venereology.
Keywords: clinical article; human tissue; clinical feature; review; cancer diagnosis; dermoscopy; skin neoplasms; tumor biopsy; retrospective study; erythema; amelanotic melanoma; cancer morphology; melanoma, amelanotic
Journal Title: Journal of the European Academy of Dermatology and Venereology
Volume: 26
Issue: 5
ISSN: 0926-9959
Publisher: Wiley Blackwell  
Date Published: 2012-05-01
Start Page: 591
End Page: 596
Language: English
DOI: 10.1111/j.1468-3083.2011.04122.x
PROVIDER: scopus
PUBMED: 21585561
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84860219717&partnerID=40&md5=b12fbfb57bd968448fd201be3021133a
Notes: --- - "Export Date: 4 June 2012" - "CODEN: JEAVE" - "Source: Scopus"
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MSK Authors
  1. Ashfaq A Marghoob
    534 Marghoob
  2. Natalia Jaimes Lopez
    21 Jaimes Lopez
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