Dermoscopy: An aid to the detection of amelanotic cutaneous melanoma metastases Journal Article

  


Authors: Jaimes, N.; Halpern, J. A.; Puig, S.; Malvehy, J.; Myskowski, P. L.; Braun, R. P.; Marghoob, A. A.
Article Title: Dermoscopy: An aid to the detection of amelanotic cutaneous melanoma metastases
Abstract: Background: The recognition of amelanotic cutaneous melanoma metastases (ACMM) remains a diagnostic challenge. Objectives: To describe and analyze the clinical and dermoscopic characteristics of ACMM. Patients and Methods: Cases of ACMM were retrospectively selected from the image databases of three dermatology centers. The clinical and dermoscopic images were combined into one database for analysis. Results: Forty-seven ACMM were observed in 18 patients. All lesions were erythematous, symmetric, dome-shaped papules or nodules appearing an average of 17 months after the diagnosis of the primary melanoma. ACMM presented as clinical outliers or as nonspecific papules found by palpation of the skin. The predominant dermoscopic feature was the presence of vascular structures, including serpentine (45%), glomerular (30%), irregular hairpin (23%) and corkscres-like vessels (19%). A few lesions also revealed crystalline (or shiny white lines) when viewed using polarized dermoscopy. Conclusion ACMM should be considered in the differential diagnosis of new or persistent skin-colored or pink papules in patients with a previous history of invasive melanoma, especially if the lesions reveal atypical vessels under dermoscopy. The presence of crystalline structures may be another clue for the detection of some ACMM. © 2012 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.
Keywords: adult; clinical article; aged; aged, 80 and over; middle aged; retrospective studies; clinical feature; cancer staging; dermoscopy; skin neoplasms; diagnosis, differential; differential diagnosis; retrospective study; epiluminescence microscopy; distant metastasis; disease severity; head and neck neoplasms; amelanotic melanoma; skin metastasis; lower extremity; upper extremity; melanoma, amelanotic; amelanotic cutaneous melanoma metastasis
Journal Title: Dermatologic Surgery
Volume: 38
Issue: 9
ISSN: 1076-0512
Publisher: Lippincott Williams & Wilkins  
Date Published: 2012-09-01
Start Page: 1437
End Page: 1444
Language: English
DOI: 10.1111/j.1524-4725.2012.02438.x
PROVIDER: scopus
PUBMED: 22587541
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84866386458&partnerID=40&md5=35f7ba09c83ee3977af35deb1e9f371b
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 1 October 2012" - "CODEN: DESUF" - "Source: Scopus"
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MSK Authors
  1. Ashfaq A Marghoob
    534 Marghoob
  2. Natalia Jaimes Lopez
    21 Jaimes Lopez
  3. Patricia Myskowski
    216 Myskowski
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