Adsorption of nucleotides on β-cyclodextrin derivative grafted chitosan Journal Article

  


Authors: Xiao, J. B.; Chen, X. Q.; Yu, H. Z.; Xu, M.
Article Title: Adsorption of nucleotides on β-cyclodextrin derivative grafted chitosan
Abstract: A novel β-cyclodextrin derivative (CCD-C) was synthesized with chitosan and carboxymethyl-β-cyclodextrin. Its structure was characterized by elemental analysis, infrared spectra analysis, and X-ray diffraction analysis. The adsorption properties for guanosine 5′-monophosphate, cytidine 5′-monophosphate and uridine 5′-monophosphate were studied. Experimental results demonstrated that CCD-C had higher adsorption capability for guanosine 5′-monophosphate, and that the adsorption capacity for guanosine 5′-monophosphate was 74.20 mg/g. The adsorption capacity was greatly influenced by pH, time and temperature. The introduction of chitosan enhanced the adsorption ability and adsorption selectivity of β-cyclodextrin for guanosine 5′-monophosphate. This novel derivative of chitosan is expected to have wide applications in the separation, concentration and analysis of nucleotides in biological samples.
Keywords: adsorption; nucleotides; chitosan; carboxymethyl-β-cyclodextrin
Journal Title: Macromolecular Research
Volume: 14
Issue: 4
ISSN: 1598-5032
Publisher: Springer  
Date Published: 2006-08-01
Start Page: 443
End Page: 448
Language: English
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-33748783627&partnerID=40&md5=3f261e3f75c1ce85d493dd9aaf6b30a2
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 4 June 2012" - "Source: Scopus"