Management of colorectal cancer in older patients Journal Article
| Authors: | Xiao, H.; Lichtman, S. M. |
| Article Title: | Management of colorectal cancer in older patients |
| Abstract: | An increasing body of evidence suggests that geriatric patients can benefit from and tolerate standard chemotherapy similarly to younger patients in the settings of both early- and advanced-stage colorectal cancer. Assessment of this unique population requires more comprehensive evaluation in addition to routine history, physical examination, and laboratory tests. Specific considerations of their physiologic functional changes will help physicians better manage these patients. Ongoing studies are now designed to better understand the decision-making process, safety profile, and efficacy of various treatment regimens in geriatric patients. |
| Keywords: | cancer chemotherapy; cancer surgery; clinical trial; drug tolerability; neutropenia; review; anamnesis; bevacizumab; fluorouracil; advanced cancer; diarrhea; drug efficacy; hypertension; united states; capecitabine; cancer adjuvant therapy; cancer staging; neurotoxicity; evidence based medicine; colorectal cancer; controlled clinical trial; allergy; leukopenia; mucosa inflammation; nausea; randomized controlled trial; stomatitis; vomiting; patient assessment; continuous infusion; cetuximab; cancer mortality; irinotecan; rash; patient care; laboratory test; folinic acid; clinical evaluation; patient safety; comorbidity; drug clearance; sepsis; aging; clinical decision making; physical examination; kidney function test; drug dose titration; oxaliplatin; hand foot syndrome; alopecia; digestive system perforation; epistaxis; life expectancy; fluoropyrimidine derivative; proteinuria; artery thrombosis; creatinine clearance; geriatric care |
| Journal Title: | Oncology (Norwalk) |
| Volume: | 20 |
| Issue: | 7 |
| ISSN: | 0890-9091 |
| Publisher: | C M P Medica LLC * The Oncology Group |
| Date Published: | 2006-01-01 |
| Start Page: | 741 |
| End Page: | 750 |
| Language: | English |
| PROVIDER: | scopus |
| PUBMED: | 16841797 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 4 June 2012" - "CODEN: OCLGE" - "Source: Scopus" |
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