Adjuvant and palliative chemotherapy for colon cancer in the elderly patient Journal Article


Authors: Power, D. G.; Lichtman, S. M.
Article Title: Adjuvant and palliative chemotherapy for colon cancer in the elderly patient
Abstract: There is an increasing body of evidence to suggest that geriatric patients can benefit from and tolerate standard chemotherapy similar to younger patients in the settings of both early and advanced stage colorectal cancer. Assessment of this expanding population requires more comprehensive evaluation in addition to routine history, physical examination, and laboratory tests. Specific considerations of their physiologic functional changes will help physicians better manage these patients. Ongoing studies are now designed to better understand the decision-making process, safety profile, and efficacy of various treatment regimens in geriatric patients. © 2008 Elsevier Inc. All rights reserved.
Keywords: cancer survival; treatment response; aged; survival rate; overall survival; drug tolerability; neutropenia; fluorouracil; advanced cancer; cancer combination chemotherapy; diarrhea; drug efficacy; drug safety; patient selection; capecitabine; cancer adjuvant therapy; neurotoxicity; cancer palliative therapy; drug eruption; allergy; creatinine; kidney failure; patient monitoring; wild type; cetuximab; irinotecan; panitumumab; cause of death; survival time; patient care; liver metastasis; folinic acid; colon cancer; clinical decision making; therapy effect; oncogene k ras; drug dose titration; oxaliplatin; hand foot syndrome; rectum cancer; geriatric patient; creatinine clearance; bleeding tendency; intestinal bleeding
Journal Title: Seminars in Colon and Rectal Surgery
Volume: 19
Issue: 4
ISSN: 1043-1489
Publisher: Elsevier Inc.  
Date Published: 2008-12-01
Start Page: 239
End Page: 246
Language: English
DOI: 10.1053/j.scrs.2008.09.009
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 17 November 2011" - "CODEN: SCRSF" - "Source: Scopus"
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MSK Authors
  1. Stuart Lichtman
    176 Lichtman
  2. Derek Gerard Power
    37 Power