Neurologic complications of cancer chemotherapy Journal Article
| Authors: | Sul, J. K.; Deangelis, L. M. |
| Article Title: | Neurologic complications of cancer chemotherapy |
| Abstract: | Neurotoxicity related to cancer therapy is a common problem in oncology practice. Neurologic side effects can be dose-limiting, can inhibit treatment, and can substantially diminish quality of life. Symptoms may appear acutely after treatment, or remotely after therapy has been discontinued. Multiple therapies may share similar toxicities, and certain agents may potentiate symptoms. When faced with the development of neurologic complaints, familiarity with the most common complications is helpful in determining the etiology of these symptoms. This review will discuss the common complications of both established and novel agents used to treat cancer. © 2006 Elsevier Inc. All rights reserved. |
| Keywords: | cancer chemotherapy; busulfan; fludarabine; hydroxyurea; thalidomide; cisplatin; fluorouracil; dose response; antineoplastic agents; capecitabine; gemcitabine; paclitaxel; cytarabine; methotrexate; temozolomide; neurotoxicity; antineoplastic agent; neoplasms; carboplatin; unindexed drug; quality of life; pain; bleeding; antineoplastic combined chemotherapy protocols; myalgia; peripheral neuropathy; extrapyramidal symptom; cyclophosphamide; vincristine; carmustine; ifosfamide; procarbazine; thiotepa; vinblastine; docetaxel; arthralgia; confusion; insomnia; papilledema; stroke; thromboembolism; thrombosis; dementia; brain disease; asparaginase; tamoxifen; retinopathy; seizure; weakness; headache; somnolence; corticosteroid; oxaliplatin; coma; psychosis; diplopia; tremor; ataxia; autonomic neuropathy; leukoencephalopathy; chlorambucil; peripheral nervous system diseases; pentostatin; spinal cord disease; blurred vision; cladribine; ototoxicity; myopathy; optic neuritis; aseptic meningitis; nervous system diseases; visual field defect; scotoma; cornea disease; retina ischemia; central nervous system diseases; cerebellum disease; arachnoiditis; optic nerve disease; cerebral blindness; psychopathy |
| Journal Title: | Seminars in Oncology |
| Volume: | 33 |
| Issue: | 3 |
| ISSN: | 0093-7754 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2006-06-01 |
| Start Page: | 324 |
| End Page: | 332 |
| Language: | English |
| DOI: | 10.1053/j.seminoncol.2006.03.006 |
| PUBMED: | 16769421 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 22" - "Export Date: 4 June 2012" - "CODEN: SOLGA" - "Source: Scopus" |
