Authors: | Shukla, N. N.; Trippett, T. M. |
Article Title: | Non-Hodgkin's lymphoma in children and adolescents |
Abstract: | Lymphoma is the third most common cancer in children and adolescents. Non-Hodgkin's lymphomas comprise a heterogeneous group of tumors with distinct pathologic and clinical characteristics. Over the past three decades, significant advancements have been made in the molecular characterization of these disorders. With the use of intensive multiagent chemotherapy, non-Hodgkin's lymphomas are now among the most successfully treated cancers in the pediatric population. Future goals of therapy include reduction of treatment duration for early-stage patients and identification of novel targets and therapeutics for advanced-stage patients. Copyright © 2006 by Current Science Inc. |
Keywords: | adolescent; cancer survival; child; treatment outcome; oncoprotein; prednisone; clinical feature; clinical trial; histopathology; mortality; review; doxorubicin; cancer combination chemotherapy; treatment duration; pathophysiology; cancer radiotherapy; disease free survival; cytarabine; methotrexate; rituximab; cancer staging; positron emission tomography; computer assisted tomography; tumor volume; cyclophosphamide; vincristine; tumor biopsy; hyperuricemia; tumor lysis syndrome; b cell lymphoma; nonhodgkin lymphoma; immunoglobulin heavy chain; bone marrow biopsy; lymphoma, non-hodgkin; folinic acid; myc protein; lactate dehydrogenase; large cell lymphoma; homeodomain protein; cancer classification; aspiration biopsy; cerebrospinal fluid analysis; immunoglobulin kappa chain; retinoblastoma protein; protein p130; burkitt lymphoma; tumor necrosis factor; allopurinol; lymphotoxin; lymphoblastoma; rasburicase; chromosome translocation 11; chromosome translocation 8; epidemiological data; nuclear matrix protein; chromosome translocation 14; chromosome translocation 2; chromosome translocation 5 |
Journal Title: | Current Oncology Reports |
Volume: | 8 |
Issue: | 5 |
ISSN: | 1523-3790 |
Publisher: | Springer |
Date Published: | 2006-09-01 |
Start Page: | 387 |
End Page: | 394 |
Language: | English |
DOI: | 10.1007/s11912-006-0062-0 |
PUBMED: | 16901400 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 7" - "Export Date: 4 June 2012" - "CODEN: CORUA" - "Source: Scopus" |