Breaking the rules of cancer Journal Article
| Authors: | Shaffer, D. R.; Pandolfi, P. P. |
| Article Title: | Breaking the rules of cancer |
| Abstract: | A cancer genetics dogma states that hematologic malignancies arise as a result of defined chromosomal translocations, whereas mutations underlie epithelial solid tumors. This rule is now broken in an analysis of chromosomal translocations in prostate cancer. © 2006 Nature Publishing Group. |
| Keywords: | mutation; exons; solid tumor; sensitivity and specificity; neoplasms; apoptosis; gene expression; models, biological; cytogenetics; genetic transcription; cell line, tumor; ewing sarcoma; prostate cancer; prostatic neoplasms; cancer genetics; hematologic malignancy; hematologic neoplasms; promyelocytic leukemia; short survey; chromosome translocation; translocation, genetic; chromosome analysis; genes, p53 |
| Journal Title: | Nature Medicine |
| Volume: | 12 |
| Issue: | 1 |
| ISSN: | 1078-8956 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2006-01-01 |
| Start Page: | 14 |
| End Page: | 15 |
| Language: | English |
| DOI: | 10.1038/nm0106-14 |
| PUBMED: | 16397543 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 10" - "Export Date: 4 June 2012" - "CODEN: NAMEF" - "Source: Scopus" |
