Long-term response with sunitinib for metastatic renal cell carcinoma Journal Article


Authors: Ronnen, E. A.; Kondagunta, G. V.; Ginsberg, M. S.; Russo, P.; Motzer, R. J.
Article Title: Long-term response with sunitinib for metastatic renal cell carcinoma
Abstract: A 65-year-old man with metastatic renal cell carcinoma developed progressive disease after treatment with interferon-α. He began treatment with sunitinib, a multitargeted tyrosine kinase inhibitor, on clinical trial. The patient achieved a partial response after two cycles of therapy, with a durable response continuing after 2 years of treatment. This case report illustrates the long-term response to sunitinib for patients with metastatic renal cell carcinoma. © 2006 Elsevier Inc. All rights reserved.
Keywords: cancer chemotherapy; aged; case report; sunitinib; diarrhea; drug dose reduction; antineoplastic agents; bone metastasis; alpha interferon; lymph node metastasis; computer assisted tomography; tumor volume; stomatitis; kidney carcinoma; kidney neoplasms; time factors; carcinoma, renal cell; drug response; remission induction; indoles; pyrroles; kidney metastasis; antidiarrheal agent; adrenal metastasis
Journal Title: Urology
Volume: 68
Issue: 3
ISSN: 0090-4295
Publisher: Elsevier Science, Inc.  
Date Published: 2006-09-01
Start Page: 672.e19
End Page: 672.e20
Language: English
DOI: 10.1016/j.urology.2006.03.042
PUBMED: 16979716
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 4" - "Export Date: 4 June 2012" - "CODEN: URGYA" - "Source: Scopus"
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  1. Ellen Arielle Ronnen
    11 Ronnen
  2. Paul Russo
    581 Russo
  3. Robert Motzer
    1243 Motzer
  4. Michelle S Ginsberg
    235 Ginsberg