Lambda's switch: Lessons from a module swap Journal Article
| Author: | Ptashne, M. |
| Article Title: | Lambda's switch: Lessons from a module swap |
| Abstract: | A recent experiment has replaced Cro, a crucial component of lambda's genetic switch, with the lac repressor (plus two lac operators). The resulting hybrid phage is viable, but a subtle phenotypic defect explains a puzzle concerning the workings of the switch. © 2006 Elsevier Ltd. All rights reserved. |
| Keywords: | dna binding protein; genetics; dna-binding proteins; metabolism; biological model; physiology; evolution, molecular; gene expression regulation; molecular evolution; short survey; models, genetic; repressor protein; repressor proteins; virus protein; viral proteins; gene expression regulation, viral; operator gene; operator regions (genetics); bacteriophage lambda; bacteriophage lambda repressor protein |
| Journal Title: | Current Biology |
| Volume: | 16 |
| Issue: | 12 |
| ISSN: | 0960-9822 |
| Publisher: | Cell Press |
| Date Published: | 2006-06-20 |
| Start Page: | R459 |
| End Page: | R462 |
| Language: | English |
| DOI: | 10.1016/j.cub.2006.05.037 |
| PUBMED: | 16782001 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 10" - "Export Date: 4 June 2012" - "CODEN: CUBLE" - "Source: Scopus" |
