Authors: | Miller, S. J.; Alam, M.; Andersen, J.; Berg, D.; Bichakjian, C. K.; Bowen, G.; Cheney, R. T.; Glass, F.; Grekin, R. C.; Grichnik, J. M.; Johnson, T. M.; Kessinger, A.; Lee, N. Y.; Lessin, S.; Lydiatt, D. D.; Margolis, L. W.; Nehal, K. S.; Nghiem, P.; Oseroff, A. R.; Rosenberg, E. W.; Shaha, A. R.; Siegle, R. J. |
Article Title: | Merkel cell carcinoma: Clinical Practice Guidelines in Oncology™ |
Abstract: | Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous tumor that combines the local recurrence rates of infiltrative non-melanoma skin cancer with the regional and distant metastatic rates of thick melanoma. The mortality rate of MCC exceeds that of melanoma, and the 5-year disease-specific survival rate is 64%. These guidelines and most biomedical literature suggest that the workup of a patient with MCC should include chest radiograph and additional studies as clinically indicated. These guidelines, which the NCCN Non-Melanoma Skin Cancer Panel developed as a supplement to those for squamous cell and basal cell skin cancer, also outline treatment strategies. © Journal of the National Comprehensive Cancer Network. |
Keywords: | cancer surgery; review; cancer recurrence; squamous cell carcinoma; cisplatin; doxorubicin; cancer risk; cancer radiotherapy; topotecan; follow-up studies; lymph node dissection; sentinel lymph node biopsy; carboplatin; melanoma; metastasis; sun exposure; skin neoplasms; etoposide; nccn clinical practice guidelines; practice guideline; oncology; algorithms; risk factor; risk assessment; adjuvant chemotherapy; merkel cell carcinoma; merkel cell tumor; carcinoma, merkel cell; nonmelanoma skin cancer; neuroendocrine sarcoma |
Journal Title: | Journal of the National Comprehensive Cancer Network |
Volume: | 4 |
Issue: | 7 |
ISSN: | 1540-1405 |
Publisher: | Harborside Press |
Date Published: | 2006-08-01 |
Start Page: | 704 |
End Page: | 712 |
Language: | English |
PUBMED: | 16884672 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 8" - "Export Date: 4 June 2012" - "Source: Scopus" |