From IMRT to IGRT: Frontierland or neverland? Journal Article


Authors: Ling, C. C.; Yorke, E.; Fuks, Z.
Article Title: From IMRT to IGRT: Frontierland or neverland?
Abstract: The recent enthusiasm for real-time image guidance in radiotherapy (IGRT) is in part due to the commercial availability of advanced on-line imaging technologies. Perhaps more important than its potential to improve conventional radiotherapy, IGRT may lead to a paradigm shift in facilitating hypo-fractionated or single-dose treatment. However, there are uncertainty regarding features and approaches of competing IGRT systems and as to whether a sub-set of the features of an ideal IGRT system would suffice for specific disease sites and clinical applications. Clinical studies are necessary for the quantification of benefit needed for evidence-based medicine (Bentzen, SM. Radiation therapy: intensity modulated, image guided, biologically optimized and evidence based. Radiat Oncol 2005;77:227-230). © 2005 Elsevier Ireland Ltd. All rights reserved.
Keywords: treatment outcome; review; neoplasms; computer assisted tomography; radiation; tomography, x-ray computed; imaging system; cost effectiveness analysis; radiotherapy, intensity-modulated; radiation dose fractionation; quantitative analysis; imaging, three-dimensional; radiotherapy planning, computer-assisted; radiotherapy, conformal; dose fractionation; image processing, computer-assisted; igrt; technology; online systems; radiotherapy, computer-assisted; computer aided design; technology, radiologic; cone-beam ct; systematic error; image-guidance; hypo-fractionation
Journal Title: Radiotherapy and Oncology
Volume: 78
Issue: 2
ISSN: 0167-8140
Publisher: Elsevier Inc.  
Date Published: 2006-02-01
Start Page: 119
End Page: 122
Language: English
DOI: 10.1016/j.radonc.2005.12.005
PUBMED: 16413622
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 51" - "Export Date: 4 June 2012" - "CODEN: RAOND" - "Source: Scopus"
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  1. Zvi Fuks
    427 Fuks
  2. Ellen D Yorke
    450 Yorke
  3. C Clifton Ling
    331 Ling