Phenolic components and antioxidant activity of Fernblock®, an aqueous extract of the aerial parts of the fern Polypodium leucotomos Journal Article
| Authors: | García, F.; Pivel, J. P.; Guerrero, A.; Brieva, A.; Martínez-Alcázar, M. P.; Caamaño-Somoza, M.; Gonzalez, S. |
| Article Title: | Phenolic components and antioxidant activity of Fernblock®, an aqueous extract of the aerial parts of the fern Polypodium leucotomos |
| Abstract: | Fernblock®, an aqueous extract of the aerial parts of the fern Polypodium leucotomos, used as raw material for topical and oral photoprotective formulations, was fractioned by HPLC and the main components with antioxidant capability were identified by means of UV spectra, electrochemical detection, and MS n. Phenolic compounds were identified as 3,4-dihydroxybenzoic acid, 4-hydroxybenzoic acid, vanillic acid, caffeic acid, 4-hydroxycinnamic acid, 4-hydroxycinnamoyl-quinic acid, ferulic acid, and five chlorogenic acid isomers. Total ferric antioxidant capacity (FRAP) of HPLC eluted fractions was measured. The results suggest that the herein identified compounds support, at least partially, the antioxidant and radical scavenging capacities of Fernblock. © 2006 Prous Science. All rights reserved. |
| Keywords: | controlled study; unclassified drug; drug activity; nonhuman; mass spectrometry; phenols; plant extracts; antioxidant; antioxidants; antioxidant activity; high performance liquid chromatography; chromatography, high pressure liquid; oxidation-reduction; drug formulation; polypodium leucotomos extract; polypodium; ferric compounds; phenol derivative; drug identification; plant components, aerial; caffeic acid; ferulic acid; ultraviolet spectroscopy; scavenger; frap; 4 hydroxybenzoic acid; parabens; electrochemical detection; fernblock; electrochemistry; hplc-electrochemical detection; hplc-mass spectrum; phenolics; 4 hydroxycinnamoylquinic acid; chlorogenic acid; para coumaric acid; vanillic acid; caffeic acids; coumaric acids |
| Journal Title: | Methods and Findings in Experimental and Clinical Pharmacology |
| Volume: | 28 |
| Issue: | 3 |
| ISSN: | 0379-0355 |
| Publisher: | Prous Science |
| Date Published: | 2006-04-01 |
| Start Page: | 157 |
| End Page: | 160 |
| Language: | English |
| DOI: | 10.1358/mf.2006.28.3.985227 |
| PUBMED: | 16810341 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 11" - "Export Date: 4 June 2012" - "CODEN: MFEPD" - "Source: Scopus" |
