Touched and moved by STAT3 Journal Article
| Authors: | Gao, S. P.; Bromberg, J. F. |
| Article Title: | Touched and moved by STAT3 |
| Abstract: | STAT3, a member of the signal transducer and activator of transcription (STAT) family of transcription factors, is a known regulator of cell motility through its transcriptional activating functions. However, new evidence suggests a novel role for non-tyrosine-phosphorylated and cytoplasmically localized STAT3 in mediating cell migration by disrupting an interaction between microtubules and one of its partners, stathmin. The association of STAT3 with stathmin potentiates microtubule polymerization and cell movement. |
| Keywords: | signal transduction; review; mouse; animal; metabolism; animals; mice; stat3 protein; cell motion; physiology; cell movement; stat3 transcription factor; stathmin |
| Journal Title: | Science's STKE : Signal Transduction Knowledge Environment |
| Volume: | 2006 |
| Issue: | 343 |
| ISSN: | 1525-8882 |
| Publisher: | American Association for the Advancement of Science |
| Date Published: | 2006-07-11 |
| Language: | English |
| DOI: | 10.1126/stke.3432006pe30 |
| PUBMED: | 16835434 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 29" - "Export Date: 4 June 2012" - "Source: Scopus" |
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