Evolving techniques in the treatment of liver colorectal metastases: Role of laparoscopy, radiofrequency ablation, microwave coagulation, hepatic arterial chemotherapy, indications and contraindications for resection, role of transplantation, and timing of chemotherapy Journal Article

  

Authors:	Fahy, B. N.; Jarnagin, W. R.
Article Title:	Evolving techniques in the treatment of liver colorectal metastases: Role of laparoscopy, radiofrequency ablation, microwave coagulation, hepatic arterial chemotherapy, indications and contraindications for resection, role of transplantation, and timing of chemotherapy
Abstract:	The management of patients who have hepatic metastases from CRC has become increasingly complex as the number of modalities that is available to treat these tumors has increased. Surgical resection remains the mainstay of treatment, when possible, and may become an option in an increasing proportion of patients that has advanced disease and previously were considered unresectable when treated with a combination of neoadjuvant systemic or hepatic arterial chemotherapy. The role of microwave coagulation and RFA can be considered only complementary to surgical resection at this point, but they may represent the best option in highly selected patients, such as those who are at high risk for extrahepatic recurrence or who are poor surgical candidates. © 2006 Elsevier Inc. All rights reserved.
Keywords:	cancer chemotherapy; cancer survival; treatment outcome; treatment response; cancer surgery; surgical technique; survival rate; clinical trial; review; cancer recurrence; cisplatin; fluorouracil; liver transplantation; antineoplastic agents; liver neoplasms; drug megadose; outcome assessment; antineoplastic agent; laparoscopy; colorectal cancer; treatment indication; diagnostic procedure; morbidity; dexamethasone; cancer mortality; irinotecan; colorectal neoplasms; liver metastasis; statistical significance; systematic review; folinic acid; mitoxantrone; intermethod comparison; hepatectomy; multivariate analysis; mitomycin; oxaliplatin; radiofrequency ablation; treatment contraindication; floxuridine; meta analysis; catheter ablation; hepatic artery; tegafur; microwaves; uracil; microwave coagulation; pirarubicin; semustine
Journal Title:	Surgical Clinics of North America
Volume:	86
Issue:	4
ISSN:	0039-6109
Publisher:	Elsevier Inc.
Date Published:	2006-08-01
Start Page:	1005
End Page:	1022
Language:	English
DOI:	10.1016/j.suc.2006.06.003
PUBMED:	16905421
PROVIDER:	scopus
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-33746915149&partnerID=40&md5=f9d493047ef84c2846f10ef723f37c5a
Notes:	--- - "Cited By (since 1996): 14" - "Export Date: 4 June 2012" - "CODEN: SCNAA" - "Source: Scopus"

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