Authors: | Deangelis, L. M.; Iwamoto, F. M. |
Article Title: | An update on therapy of primary central nervous system lymphoma |
Abstract: | The most important advance in primary central nervous system (CNS) lymphoma treatment has been the convincing data that high-dose methotrexate-based chemotherapy regimens improve survival compared to historical controls treated with radiotherapy alone. However, the optimal treatment approach is still unclear and therapy can be associated with long-term neurotoxicity. Current research focuses on maximizing survival while minimizing neurologic sequelae. |
Keywords: | survival rate; mortality; review; multimodality cancer therapy; combined modality therapy; methotrexate; central nervous system tumor; central nervous system neoplasms; lymphoma |
Journal Title: | Hematology-American Society of Hematology Education Program |
ISSN: | 1520-4391 |
Publisher: | American Society of Hematology |
Date Published: | 2006-01-01 |
Start Page: | 311 |
End Page: | 316 |
Language: | English |
PUBMED: | 17124077 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 8" - "Export Date: 4 June 2012" - "Source: Scopus" |