Bone grafts and substitutes Journal Article


Authors: Cutter, C. S.; Mehrara, B. J.
Article Title: Bone grafts and substitutes
Abstract: Bone is a complex organ system that provides structural support for the human body while also serving an important protective function for the internal organs. It is estimated that over 500,000 bone-grafting procedures are performed annually in the United States. These procedures have stimulated the pursuit of novel biomaterials with ideal properties. Key goals are to develop a biomaterial to replace bone that is inexpensive, biocompatible, radiolucent, resistant to infection, compressible, and replaced by host bone. The purpose of this review is to present the uses of commercially available bone grafts substitutes including allografts, calcium sulfates, calcium phosphates, and polymer materials. Descriptions of these biomaterials are provided in the context of their applications including craniofacial surgery, neurosurgery, fracture repair, dental and periodontal procedures, as well as pediatric reconstruction. © 2006 by Begell House, Inc.
Keywords: bone graft; fracture; bone transplantation; transplantation, homologous; review; plastic surgery; neurosurgery; bone; compression; biocompatibility; craniofacial surgery; sodium chloride; biological organs; polymer; pediatrics; bone cement; prostheses and implants; bone allograft; bone prosthesis; biomaterial; bone conduction; calcium phosphate; glycerol; infection resistance; gelatin; calcium sulfate; biomaterials; pediatric surgery; bone substitutes; dental surgery; bone grafts; osteoconduction; osteoinduction; calcium compounds; roseolic acid; periodontics
Journal Title: Journal of Long-Term Effects of Medical Implants
Volume: 16
Issue: 3
ISSN: 1050-6934
Publisher: Begell House, Inc  
Date Published: 2006-01-01
Start Page: 249
End Page: 260
Language: English
PUBMED: 17073567
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 9" - "Export Date: 4 June 2012" - "CODEN: JLEIE" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Carole Suzanne Cutter
    3 Cutter
  2. Babak Mehrara
    448 Mehrara