Laparoscopic and hand-assisted laparoscopic splenectomy for recurrent and persistent ovarian cancer Journal Article

  


Authors: Chi, D. S.; Abu-Rustum, N. R.; Sonoda, Y.; Im, H. B.; Jhamb, N.; D'Angelica, M.; Rim, M.; Dupont, J.; Barakat, R. R.
Article Title: Laparoscopic and hand-assisted laparoscopic splenectomy for recurrent and persistent ovarian cancer
Abstract: Objective.: Prolonged survival in patients with recurrent ovarian cancer isolated to the spleen has been demonstrated after successful splenectomy. The purpose of this study was to report the outcomes of a series of patients who underwent splenectomy for persistent or recurrent ovarian cancer via laparoscopy or hand-assisted laparoscopy. Methods.: We reviewed the charts of all patients who underwent laparoscopic or hand-assisted laparoscopic splenectomy for presumed persistent or recurrent ovarian cancer. Demographic, clinical, pathologic, and follow-up information was abstracted. Results.: Six patients underwent laparoscopy or hand-assisted laparoscopy for presumed ovarian cancer involving the spleen. In 5 of the 6 cases, laparoscopic or hand-assisted laparoscopic splenectomy was successfully performed. For the 5 laparoscopic cases, operative times varied from 155 to 315 min, and estimated blood loss ranged from 50 to 300 ml. There were no perioperative mortalities or significant complications. Hospitalization lasted from 3 to 5 days. Four patients are alive with no evidence of disease at 2-84 months from the splenectomy, while 1 patient died of disease 20 months after the procedure. The sixth patient underwent initial hand-assisted laparoscopy, and the case was immediately converted to laparotomy for resection of peritoneal carcinomatosis. Conclusion.: Laparoscopic and hand-assisted laparoscopic splenectomies are safe and feasible in the management of patients with presumed persistent or recurrent ovarian cancer. Larger studies are necessary and eagerly awaited to help determine the long-term risks and benefits as well as the most appropriate candidates and selection criteria. © 2005 Elsevier Inc. All rights reserved.
Keywords: adult; clinical article; treatment outcome; aged; aged, 80 and over; middle aged; cancer surgery; surgical technique; splenectomy; risk benefit analysis; cancer patient; recurrent cancer; follow up; laparoscopy; laparoscopic surgery; laparotomy; ovarian neoplasms; demography; ovary cancer; neoplasm recurrence, local; spleen; bleeding; medical record review; postoperative complication; cause of death; hospitalization; medical information; operation duration; surgical risk; surgical mortality; perioperative period; carcinomatous peritonitis; recurrent ovarian cancer; hand-assisted laparoscopy
Journal Title: Gynecologic Oncology
Volume: 101
Issue: 2
ISSN: 0090-8258
Publisher: Elsevier Inc.  
Date Published: 2006-05-01
Start Page: 224
End Page: 227
Language: English
DOI: 10.1016/j.ygyno.2005.10.037
PUBMED: 16337997
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-33646390682&partnerID=40&md5=574694d17157bf1cac8887ff80d0329f
Notes: --- - "Cited By (since 1996): 9" - "Export Date: 4 June 2012" - "CODEN: GYNOA" - "Source: Scopus"
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MSK Authors
  1. Richard R Barakat
    629 Barakat
  2. Dennis S Chi
    707 Chi
  3. Yukio Sonoda
    472 Sonoda
  4. Jakob Dupont
    65 Dupont
  5. Nadeem Abu-Rustum
    888 Abu-Rustum
  6. Michael D'Angelica
    777 D'Angelica
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