Primary treatment of the anterior vocal commissure squamous carcinoma Journal Article


Authors: Bradley, P. J.; Rinaldo, A.; Suárez, C.; Shaha, A. R.; René Leemans, C.; Langendijk, J. A.; Patel, S. G.; Ferlito, A.
Article Title: Primary treatment of the anterior vocal commissure squamous carcinoma
Abstract: Squamous cell carcinoma may involve the anterior commissure (AC) area of the laryngeal glottis, and can be grouped morphologically into four groups; (1) tumor confined to the AC, (2) tumor involving one cord and the AC, (3) tumor involving the AC and a portion of both vocal cords, and (4) tumor involving a greater part of one cord and crossing over to involve a variable length of the other cord. Some of these patients when evaluated by imaging, either CT and/or MRI, may demonstrate thyroid cartilage erosion or involvement, thereby upstaging a T1a, T1b into a T3 or a T4 glottic cancer. The majority of patients treated by radiotherapy have only been staged clinically, and hence a failure or recurrence rate of 15%. In patients treated surgically by endoscopic or external surgery, the local recurrence rates are similar at 15%. Therefore, future reporting of patients treated with AC involvement should be staged radiologically, to include CT or MRI, and documentation of the treatment results be reported in subgroups, according to whether there is no cartilage involvement, inner-table cartilage erosion, or through-and-through cartilage invasion. Should endoscopic cordectomy be used, then the type of surgery performed should be based on the classification as suggested by the European Laryngological Society. The use of the above recommendations would allow for more meaningful results to be reported and for cause specific analysis of failure of treatment techniques applied. © Springer-Verlag 2006.
Keywords: cancer surgery; surgical technique; treatment failure; review; larynx carcinoma; squamous cell carcinoma; carcinoma, squamous cell; laryngeal neoplasms; nuclear magnetic resonance imaging; cancer diagnosis; computer assisted tomography; radiotherapy; cancer invasion; endoscopic surgery; medical society; vocal cords; surgery; larynx cancer; glottis; laryngoscopy; anterior commissure; primary treatment; larynx cartilage; chondropathy
Journal Title: European Archives of Oto-Rhino-Laryngology
Volume: 263
Issue: 10
ISSN: 0937-4477
Publisher: Springer  
Date Published: 2006-10-01
Start Page: 879
End Page: 888
Language: English
DOI: 10.1007/s00405-006-0138-3
PUBMED: 16909217
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 19" - "Export Date: 4 June 2012" - "CODEN: EAOTE" - "Source: Scopus"
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  1. Ashok R Shaha
    697 Shaha
  2. Snehal G Patel
    412 Patel