Esophageal cancer: Clinical Practice Guidelines in Oncology™ Journal Article
| Authors: | Ajani, J.; Bekaii-Saab, T.; D'Amico, T. A.; Fuchs, C.; Gibson, M. K.; Goldberg, M.; Hayman, J. A.; Ilson, D. H.; Javle, M.; Kelley, S.; Kurtz, R. C.; Locker, G. Y.; Meropol, N. J.; Minsky, B. D.; Orringer, M. B.; Osarogiagbon, R. U.; Posey, J. A.; Roth, J.; Sasson, A. R.; Swisher, S. G.; Wood, D. E.; Yen, Y. |
| Article Title: | Esophageal cancer: Clinical Practice Guidelines in Oncology™ |
| Abstract: | Esophageal cancer is a major health hazard in many parts of the world. The incidence of adenocarcinoma is increasing in white men, particularly in the nonendemic areas such as North America and many Western European countries. Barrett's metaplasia, gastroesophageal reflux, hiatal hernia, and obesity are believed to be contributing factors. In addition, the most common location of esophageal carcinoma has shifted to the lower third of the esophagus. Unfortunately, esophageal carcinoma is often diagnosed late and, therefore, most therapeutic approaches are palliative. Advances have been made in staging procedures and therapeutic approaches. The guidelines emphasize that palpable advances have been made in the treatment of locoregional esophageal carcinoma. Similarly, endoscopic palliation of esophageal carcinoma has improved substantially because of improving technology. New chemotherapeutic agents are on the horizon, including antireceptor agents, vaccines, gene therapy, and anti-angiogenic agents. The panel expects numerous future advances in the treatment of esophageal carcinoma. © Journal of the National Comprehensive Network. |
| Keywords: | cancer chemotherapy; treatment outcome; cancer surgery; surgical technique; clinical trial; drug activity; neutropenia; review; salvage therapy; squamous cell carcinoma; cisplatin; doxorubicin; fluorouracil; disease classification; gemcitabine; paclitaxel; cancer radiotherapy; combined modality therapy; chemotherapy; methotrexate; cancer staging; cancer incidence; clinical practice; adenocarcinoma; carboplatin; morbidity; nccn clinical practice guidelines; patient assessment; practice guideline; oncology; docetaxel; irinotecan; systematic review; proton pump inhibitor; gefitinib; medical society; brachytherapy; bleomycin; surgery; intermethod comparison; vindesine; endoscopic therapy; resection; taxane derivative; laser surgery; navelbine; mitomycin; oxaliplatin; esophagus cancer; radiodiagnosis; chemoradiation; meta analysis; lower esophagus sphincter; omeprazole; dysplasia; antihistaminic agent; mitoguazone; esophageal carcinoma; lansoprazole; esomeprazole; barrett esophagus; pantoprazole; rabeprazole; lobaplatin; nedaplatin |
| Journal Title: | Journal of the National Comprehensive Cancer Network |
| Volume: | 4 |
| Issue: | 4 |
| ISSN: | 1540-1405 |
| Publisher: | Harborside Press |
| Date Published: | 2006-04-01 |
| Start Page: | 328 |
| End Page: | 347 |
| Language: | English |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 18" - "Export Date: 4 June 2012" - "Source: Scopus" |
