Modern approaches to localized cancer of the esophagus Journal Article
| Authors: | Glasgow, R. E.; Ilson, D. H.; Hayman, J. A.; Gerdes, H.; Mulcahy, M. F.; Ajani, J. A. |
| Article Title: | Modern approaches to localized cancer of the esophagus |
| Abstract: | The clinical spectrum of esophageal cancer has changed dramatically over the past couple of decades. Most notably, a profound rise in esophageal adenocarcinoma and decrease in the incidence of squamous carcinomas have occurred. An understanding of the factors that influence survival for patients with localized esophageal cancer has evolved concomitantly with these changes in epidemiology. Significant advancement in endoscopic and radiographic staging allows for more selective use of treatment modalities. The treatment of localized esophageal cancer mandates a multidisciplinary approach, with treatment tailored to disease extent, location, histology, and an accurate assessment of pretreatment staging. Despite these improvements in the staging and use of multimodality therapy, only modest improvements in patient survival have been observed. This article summarizes these modern approaches to localized cancer of the esophagus. © JNCCN-Journal of the National Comprehensive Cancer Network. |
| Keywords: | cancer chemotherapy; cancer survival; treatment outcome; cancer surgery; histopathology; mortality; review; cancer localization; squamous cell carcinoma; cisplatin; fluorouracil; advanced cancer; cancer combination chemotherapy; cancer growth; patient selection; capecitabine; paclitaxel; cancer radiotherapy; postoperative care; preoperative care; radiation dose; chemotherapy; cancer staging; lymph node metastasis; cancer diagnosis; cancer grading; laparotomy; sensitivity and specificity; carboplatin; tumor volume; morbidity; docetaxel; irinotecan; cancer invasion; folinic acid; computer assisted emission tomography; surgery; esophagus resection; epirubicin; radiation therapy; perioperative period; aspiration biopsy; endoscopic biopsy; oxaliplatin; radiofrequency ablation; esophagus cancer; esophageal adenocarcinoma; photodynamic therapy; fluoropyrimidine; lymphadenopathy; chemoradiotherapy; esophageal cancer; endoscopic echography; lower esophagus sphincter; esophagus biopsy; meta analysis (topic); barrett esophagus; endoscopic mucosal resection; colon interposition; esophagoscopy; stomach muscle |
| Journal Title: | Journal of the National Comprehensive Cancer Network |
| Volume: | 9 |
| Issue: | 8 |
| ISSN: | 1540-1405 |
| Publisher: | Harborside Press |
| Date Published: | 2011-08-01 |
| Start Page: | 902 |
| End Page: | 911 |
| Language: | English |
| PROVIDER: | scopus |
| PUBMED: | 21900220 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 October 2011" - "Source: Scopus" |
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