Management of post-chemotherapy extra-retroperitoneal residual masses Journal Article
| Authors: | Carver, B. S.; Sheinfeld, J. |
| Article Title: | Management of post-chemotherapy extra-retroperitoneal residual masses |
| Abstract: | Introduction: Testicular cancer is the most common cancer in men age 20-35 years and accounts for approximately 1% of all male malignancies. While the retroperitoneum is often the first and only site of metastatic disease, approximately 40% of patients presenting with metastatic disease will have disease involving extra-retroperitoneal sites. Materials and methods: A medline review was conducted to evaluate peer-reviewed articles reporting on the outcome of patients with germ cell tumors and extra-retroperitoneal metastases. Results: Following chemotherapy, approximately 70% of patients will have residual masses in the retroperitoneum and several series demonstrate that approximately 50% of patients will harbor teratoma or viable GCT in the retroperitoneum. Additionally, up to 35% of patients will have radiographic evidence of extra-retroperitoneal (ERP) masses after chemotherapy. Conclusion: In this manuscript, we will review the current role of surgery for patients with post-chemotherapy residual ERP metastases. © Springer-Verlag 2009. |
| Keywords: | cisplatin; multimodality cancer therapy; combined modality therapy; antineoplastic agent; neoplasm; metastasis; etoposide; antineoplastic combined chemotherapy protocols; pathology; testis tumor; testicular neoplasms; bleomycin; teratoma; surgical resection; testicular cancer; bep protocol; vp p protocol; vp-p protocol; retroperitoneal tumor; neoplasms, germ cell and embryonal; retroperitoneal neoplasms |
| Journal Title: | World Journal of Urology |
| Volume: | 27 |
| Issue: | 4 |
| ISSN: | 0724-4983 |
| Publisher: | Springer |
| Date Published: | 2009-08-01 |
| Start Page: | 489 |
| End Page: | 492 |
| Language: | English |
| DOI: | 10.1007/s00345-009-0412-2 |
| PUBMED: | 19373472 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 3" - "Export Date: 30 November 2010" - "Source: Scopus" |
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