Postchemotherapy surgery for germ cell tumors of the testis Journal Article
| Authors: | Carver, B. S.; Sheinfeld, J. |
| Article Title: | Postchemotherapy surgery for germ cell tumors of the testis |
| Abstract: | Purpose of review: To summarize the surgical management of metastatic germ cell tumors of the testis, highlighting the indications for surgery and controversies surrounding the integration of surgery. Recent findings: The multidisciplinary approach to the management of germ cell tumors of the testis has resulted in survival rates of greater than 90% overall. However, controversies exist regarding the surgical management of patients who achieve a complete radiographic response following chemotherapy as well as the appropriate retroperitoneal templates to use in the postchemotherapy setting. Recent data have demonstrated that despite a complete radiographic response, approximately 30% of patients will harbor either viable cancer or teratoma in the retroperitoneum. With advances in nerve-sparing techniques and the probability of disease extending beyond the anatomic boundaries of modified templates, a bilateral nerve-sparing retroperitoneal lymph node dissection is the treatment of choice for patients with metastatic nonseminoma, initially treated with chemotherapy. Summary: Postchemotherapy surgical resection of all sites of residual disease remains a critical component to the multidisciplinary management of metastatic testicular cancer. © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins. |
| Keywords: | cancer chemotherapy; cancer survival; cancer surgery; surgical technique; review; cancer radiotherapy; chemotherapy; lymph node dissection; treatment indication; tumor marker; postoperative complication; testis tumor; bleomycin; testis cancer; germ cell tumor; seminoma; retroperitoneal lymph node dissection; retroperitoneal cancer; testis nonseminoma cancer |
| Journal Title: | Current Opinion in Oncology |
| Volume: | 23 |
| Issue: | 3 |
| ISSN: | 1040-8746 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2011-05-01 |
| Start Page: | 271 |
| End Page: | 274 |
| Language: | English |
| DOI: | 10.1097/CCO.0b013e32834579d9 |
| PROVIDER: | scopus |
| PUBMED: | 21415749 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 23 June 2011" - "CODEN: CUOOE" - "Source: Scopus" |
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