Managing incidentally diagnosed isolated factor VII deficiency perioperatively: A brief expert consensus report Journal Article
| Authors: | Sheth, S.; Soff, G.; Mitchell, B.; Green, D.; Kaicker, S.; Fireman, F.; Tugal, O.; Guarini, L.; Giardina, P.; Aledort, L. |
| Article Title: | Managing incidentally diagnosed isolated factor VII deficiency perioperatively: A brief expert consensus report |
| Abstract: | While isolated factor VII (FVII) deficiency is being more frequently diagnosed owing to improved preoperative screening procedures, there is no specific guideline for perioperative management of such patients. To complicate the issue, FVII activity levels seem to correlate less well with the risk of hemorrhage than the patient's past and family bleeding history do. We have devised expert consensus recommendations for managing such patients perioperatively, taking into consideration the personal and family bleeding history, the FVII activity level and the inherent bleeding risk of the procedure itself. We hope that clinicians will find this a useful tool in the decision-making process, thereby limiting the use of recombinant factor VIIa to those who need it most, and preventing possible thrombotic complications in those without a strong indication for its use. © 2012 Expert Reviews Ltd. |
| Keywords: | gastrointestinal hemorrhage; consensus; bleeding; prothrombin time; disease severity; vitamin supplementation; perioperative period; immunofluorescence test; incidental finding; postoperative hemorrhage; decision making; chromosome 13; brain hemorrhage; hemostasis; hemophilia a; perioperative care; vitamin k group; recombinant blood clotting factor 7a; fresh frozen plasma; perioperative nursing; qualitative diagnosis; fvii deficiency; perioperative management algorithm; variable bleeding; antifibrinolytic agent; blood clotting factor 7 deficiency; alexander disease; factor vii; factor vii deficiency |
| Journal Title: | Expert Review of Hematology |
| Volume: | 5 |
| Issue: | 1 |
| ISSN: | 1747-4086 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 2012-02-01 |
| Start Page: | 47 |
| End Page: | 50 |
| Language: | English |
| DOI: | 10.1586/ehm.11.76 |
| PROVIDER: | scopus |
| PUBMED: | 22272705 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 March 2012" - "Source: Scopus" |
