Facile synthesis and altered ionization efficiency of diverse N ε-alkyllysine-containing peptides Journal Article
| Authors: | Chakraborty, D.; Islam, K.; Luo, M. |
| Article Title: | Facile synthesis and altered ionization efficiency of diverse N ε-alkyllysine-containing peptides |
| Abstract: | Protein lysine methylation is a biologically-important posttranslational modification. Given the increased use of alkyllysine-containing peptides to study protein methylation, we describe an efficient solid-phase synthesis to access various alkyllysine-containing peptides. As an exemplary application, we evaluated how ionization efficiency of the alkyllysine peptides affects mass spectrometric analysis. © 2012 The Royal Society of Chemistry. |
| Keywords: | mass spectrometry; protein synthesis; protein methylation; alkyl group; ionization; lysine derivative |
| Journal Title: | Chemical Communications |
| Volume: | 48 |
| Issue: | 10 |
| ISSN: | 1359-7345 |
| Publisher: | Royal Society of Chemistry |
| Date Published: | 2012-02-01 |
| Start Page: | 1514 |
| End Page: | 1516 |
| Language: | English |
| DOI: | 10.1039/c1cc14711k |
| PROVIDER: | scopus |
| PUBMED: | 21959946 |
| PMCID: | PMC3573693 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 March 2012" - "CODEN: CHCOF" - "Source: Scopus" |
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