Evolving medical management of erectile dysfunction: recommendations from the Fifth International Consultation on Sexual Medicine (ICSM 2024) Journal Article
| Authors: | Stern, N.; Bajic, P.; Campbell, J.; Capogrosso, P.; Domes, T.; Miranda, E. P.; Mulhall, J. P.; Nascimento, B.; Pignanelli, M.; Pastuszak, A. W.; Brock, G. |
| Article Title: | Evolving medical management of erectile dysfunction: recommendations from the Fifth International Consultation on Sexual Medicine (ICSM 2024) |
| Abstract: | Introduction: Treatment of erectile dysfunction is based on pharmacotherapy for most patients. Aim: To review the current data on pharmacotherapy for erectile dysfunction based on efficacy, psychosocial outcomes, and safety outcomes. Methods: A review of the literature was undertaken by the committee members. All related articles were critically analyzed and discussed, and consensus statements were developed after presentation at the 2024 ICSM. Results: Eight recommendations are provided with the corresponding level of evidence and grade of recommendation. Conclusions: The management of erectile dysfunction should be personalized to address the psychosocial needs and expectations of both the patient and their partner. PDE5 inhibitors remain the first-line treatment for most men, while intracavernosal injections, vacuum erection devices, and penile prostheses serve as second-line options, with treatment decisions guided by patient preferences. Key recommendations are summarized in table 1. |
| Keywords: | sexual behavior; intracavernosal injection therapy; placebo-controlled trial; quality-of-life; benign prostatic hyperplasia; spinal-cord-injury; sildenafil citrate viagra((r)); male; penile erection/physiology; erectile dysfunction/prevention & control*; practice guidelines as topic*; dose oral sildenafil; once-a-day; orodispersible vardenafil formulation; melanocortin receptor agonist |
| Journal Title: | Sexual Medicine Reviews |
| ISSN: | 2050-0513 |
| Publisher: | International Society for Sexual Medicine |
| Publication status: | Online ahead of print |
| Date Published: | 2025-01-01 |
| Online Publication Date: | 2025-01-01 |
| Language: | English |
| ACCESSION: | WOS:001543233100001 |
| DOI: | 10.1093/sxmrev/qeaf035 |
| PROVIDER: | wos |
| Notes: | Review; Early Access -- Source: Wos |
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