Abstract: |
Percutaneous coronary intervention (PCI) during pregnancy presents unique challenges due to physiological cardiovascular adaptations and concerns regarding maternal and fetal safety. This comprehensive review examines the current understanding of PCI in pregnancy, including pathophysiology, indications, technical considerations, outcomes, and management approaches. Despite being rare, cardiovascular disease remains the leading cause of maternal mortality in developed countries, with acute coronary syndrome increasing in frequency among pregnant women. The management of acute coronary syndrome in pregnancy requires a multidisciplinary approach focusing on maternal safety while minimizing fetal risks. Current evidence supports the use of PCI as the preferred revascularization strategy for appropriate indications during pregnancy, with specific procedural modifications to minimize radiation exposure and optimize medication selection. This review synthesizes contemporary literature to provide evidence-based recommendations for the management of pregnant patients requiring coronary intervention. © 2025 Wolters Kluwer Health, Inc. All rights reserved. |