Brentuximab vedotin plus chemotherapy for the treatment of front-line systemic anaplastic large cell lymphoma: Subgroup analysis of the ECHELON-2 study at 5 years’ follow-up Correspondence


Authors: Domingo-Doménech, E.; Bosi, B.; Illidge, T.; Horwitz, S.; Trümper, L.; Iyer, S.; Advani, R.; Bartlett, N. L.; Christensen, J. H.; Kim, W. S.
Title: Brentuximab vedotin plus chemotherapy for the treatment of front-line systemic anaplastic large cell lymphoma: Subgroup analysis of the ECHELON-2 study at 5 years’ follow-up
Abstract: Trial registration: ClinicalTrials.gov number: NCT01777152 © 2025 Elsevier B.V., All rights reserved.
Keywords: adult; cancer chemotherapy; treatment outcome; aged; middle aged; major clinical study; prednisone; clinical trial; constipation; mortality; neutropenia; doxorubicin; cancer combination chemotherapy; diarrhea; drug efficacy; follow up; follow-up studies; antineoplastic agent; letter; progression free survival; sensory neuropathy; nausea; randomized controlled trial; vomiting; antineoplastic combined chemotherapy protocols; peripheral neuropathy; cyclophosphamide; vincristine; pathology; peripheral t cell lymphoma; proportional hazards model; multicenter study; recurrent disease; clinical effectiveness; phase 3 clinical trial; drug therapy; microtubule; non-hodgkin lymphoma; log rank test; anaplastic lymphoma kinase; international prognostic index; post hoc analysis; institutional review; lymphoma, large-cell, anaplastic; anaplastic large cell lymphoma; overall response rate; brentuximab vedotin; humans; human; male; female; prognostic assessment
Journal Title: Blood Cancer Journal
Volume: 15
ISSN: 2044-5385
Publisher: Nature Publishing Group  
Date Published: 2025-08-01
Start Page: 129
Language: English
DOI: 10.1038/s41408-025-01329-2
PUBMED: 40750774
PROVIDER: scopus
PMCID: PMC12317119
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Source: Scopus
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  1. Steven M Horwitz
    668 Horwitz