Hybrid imaging and radionuclide therapy of neuroendocrine tumors Book Section
| Authors: | Volterrani, D.; Bodei, L.; Guidoccio, F. |
| Editors: | Volterrani, D.; Erba, P. A.; Carrió, I.; Strauss, H. W.; Mariani, G. |
| Article/Chapter Title: | Hybrid imaging and radionuclide therapy of neuroendocrine tumors |
| Abstract: | Neuroendocrine tumors (NETs) constitute a heterogeneous group of rare tumors that arise from cells of the neuroendocrine system. The term “neuroendocrine” relates to the ability of these cells to produce and store amines and peptide hormones produced by both the endocrine system and the nervous systems: gastrin, insulin, serotonin, somatostatin, glucagon, pancreatic polypeptide, vasoactive intestinal peptide (VIP), catecholamines, ACTH, GH, prolactin, FSH, LH, TSH, and PTH. Although NETs differ widely in their biology and clinical presentation, they share the capability to produce certain biological compounds (chromogranins and synaptophysin) that are considered specific markers of neuroendocrine cells [1]. © 2025 Elsevier B.V., All rights reserved. |
| Keywords: | medical imaging; tumors; nuclear medicine; medical computing; biomedical engineering; neuroendocrine tumors; hormones; biochemical engineering; endocrinology; positive ions; radionuclide therapy; peptide receptor; scintillation; somatostatin receptors; peptide receptor radionuclide therapy; 111in-pentetreotide scintigraphy; 123i-mibg scintigraphy; 177lu-dota-tate/177lu-dota-noc/177lu-dota-toc; 90y-dota-tate/90y-dota-noc/90y-dota-toc; expression of somatostatin receptors; neuramine uptake; pet/ct with 18f-dopa pet/ct; pet/ct with [18f]fdg; petc/ct with 68ga-dota-tate/68ga-dota-noc/68ga-dota-toc; expression of somatostatin receptor; in-pentetreotide |
| Book Title: | Nuclear Medicine Textbook: Methodology and Clinical Applications |
| ISBN: | 978-3-319-95563-6 |
| Publisher: | Springer Science + Business Media, LLC |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2019-01-01 |
| Start Page: | 767 |
| End Page: | 784 |
| Language: | English |
| DOI: | 10.1007/978-3-319-95564-3_29 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 29, part of "Part II - Organ/Apparatus-Specific Applications" -- Source: Scopus |
