Radionuclide imaging of cardiovascular disease Book Section
| Authors: | Bauckneht, M.; Ticconi, F.; Piva, R.; Slart, R. H. J. A.; Nieri, A.; Morbelli, S.; Erba, P. A.; Marini, C.; Strauss, H. W.; Sambuceti, G. |
| Editors: | Volterrani, D.; Erba, P. A.; Carrió, I.; Strauss, H. W.; Mariani, G. |
| Article/Chapter Title: | Radionuclide imaging of cardiovascular disease |
| Abstract: | Multiple imaging modalities are clinically available for evaluation of global and regional cardiac function, determination of regional myocardial perfusion, and evaluation of coronary anatomy, including SPECT with CT, PET with CT, multi-detector computed tomography (MDCT), magnetic resonance imaging (MRI), and ultrasound. Emblematic of this revolution is the capability of cardiac MDCT to integrate evaluation of coronary artery anatomy with noninvasive assessment of myocardial perfusion and contractile function [1]. MDCT still needs to be technically optimized, particularly to identify small changes in myocardial perfusion, which can be done reproducibly with radionuclide techniques [2]. On the other hand, despite proven clinical efficacy in the detection of CAD (primarily based on the presence of calcium in the coronary arteries), MDCT imaging performs suboptimally in the noninvasive characterization of multivessel CAD. On the other hand, the specificity of nuclear imaging is improved by attenuation correction. Accordingly, multimodality SPECT/CT or PET/CT approach is the current standard for evaluating myocardial perfusion. © 2025 Elsevier B.V., All rights reserved. |
| Keywords: | pathophysiology; positron emission tomography; magnetic resonance imaging; automation; blood; medical imaging; adenosine; heart failure; diagnosis; function evaluation; coronary artery disease; heart; hemodynamics; diseases; blood vessels; biomedical engineering; pet/ct; multidetector computed tomography; myocardial perfusion; cardiology; defects; spect; spect/ct; blood vessel prostheses; vasculitis; dipyridamole; dobutamine; angina; cardiac amyloidosis; myocarditis; artificial heart; implants (surgical); infective endocarditis; perfusion imaging; pharmacologic stress testing; 123i-mibg; myocardial ischemia; noninvasive medical procedures; ventricular assist device; stress testing; left ventricular; acute myocardial infarction; 99mtc-sestamibi; 201tl-chloride; [18f]fdg pet/ct; rubidium-82; [13n]ammonia; coronary circulation; myocardial blood flow; 82sr/82rb generator; 99mtc-hmpao-wbc spect/ct; 99mtc-tetrofosmin; acute pericarditis; cardiac sarcoidosis; cardiovascular implantable electronic devices; exercise stress testing; heart-to-mediastinum ratio; implantable left ventricular assist devices; large vessel vasculitis; myocardial viability; native valve endocarditis; pathophysiology of coronary circulation; prosthetic valve endocarditis; regadenoson; rest myocardial perfusion imaging; stress myocardial perfusion imaging; vascular prosthetic infection; [15o]water; valves (mechanical); acute pericarditi; anginum; fdg-pet-ct; heart-to-mediastinum ratios; implantable leave ventricular assist device; myocarditi; native valve endocarditi; prosthetic valve endocarditi |
| Book Title: | Nuclear Medicine Textbook: Methodology and Clinical Applications |
| ISBN: | 978-3-319-95563-6 |
| Publisher: | Springer Science + Business Media, LLC |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2019-01-01 |
| Start Page: | 449 |
| End Page: | 497 |
| Language: | English |
| DOI: | 10.1007/978-3-319-95564-3_20 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 20, part of "Part II - Organ/Apparatus-Specific Applications" -- Source: Scopus |
