Korea, Japan, Europe, and the United States: Why are guidelines for gastric cancer different? Review
| Authors: | Stroobant, E. E.; Kong, S. H.; Bencivenga, M.; Kinoshita, T.; Kim, T. H.; Sano, T.; de Manzoni, G.; Yang, H. K.; Kitagawa, Y.; Strong, V. E. |
| Review Title: | Korea, Japan, Europe, and the United States: Why are guidelines for gastric cancer different? |
| Abstract: | As a global health concern, gastric cancer management has been systematized by individual countries and regions into regimented guidelines. To explore international differences, we examined the guidelines of Korea, Japan, Europe, and the United States. Guidelines are created by experts in the field, focusing on evidence-based recommendations to standardize and improve patient care, but the methodology for guideline creation, incorporation of new innovations, and review differs significantly. National and regional differences within the guidelines are apparent, stemming from various factors including local incidence, stage, presentation, patient preferences, and governmental influences. Differences include the use of neoadjuvant chemotherapy, criteria for endoscopic resection, and extent of lymphadenectomy. Nonetheless, fundamental treatment principles remain universal, and the goals of national guidelines are uniform: standardizing patient care, providing the highest quality treatments, incorporating cutting-edge clinical trial results, and consensus in guidelines to help formulate governmental policies. This review highlights how the guidelines are constructed, the unique elements of each guideline, how they differ, and why they differ. © The Author(s) under exclusive licence to The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2025. |
| Keywords: | review; united states; cancer patient; comparative study; cancer staging; antineoplastic agent; cancer incidence; lymph node dissection; practice guideline; europe; health care quality; patient care; endoscopic surgery; stomach cancer; neoadjuvant chemotherapy; japan; public policy; gastric cancer; patient preference; process development; korea; practice guidelines; international perspectives; human; national guidelines |
| Journal Title: | Gastric Cancer |
| Volume: | 28 |
| Issue: | 4 |
| ISSN: | 1436-3291 |
| Publisher: | Springer |
| Date Published: | 2025-07-01 |
| Start Page: | 559 |
| End Page: | 568 |
| Language: | English |
| DOI: | 10.1007/s10120-025-01613-x |
| PUBMED: | 40240698 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF. Corresponding MSK author is Vivian E. Strong -- Source: Scopus |
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