Patient-reported quality of life and esthetic satisfaction continues to improve for 1-year after Mohs surgery: A multicenter prospective cohort study Journal Article


Authors: Veldhuizen, I. J.; Dusza, S. W.; Kuo, A.; Aleisa, A.; Blue, E.; Adhikari, S.; Nadir, U.; Le, K.; Kazemi, S.; Sutton, A. V.; Nijhawan, R. I.; Eisen, D. B.; Rossi, A. M.; Srivastava, D.; Wysong, A.; Nehal, K. S.; Lee, E. H.
Article Title: Patient-reported quality of life and esthetic satisfaction continues to improve for 1-year after Mohs surgery: A multicenter prospective cohort study
Abstract: Background: Despite the growth in patient-centered care, multicenter prospective studies investigating satisfaction after skin cancer surgery are limited. Objective: To assess trends in esthetic satisfaction, symptoms, and quality of life over 1 year in facial skin cancer patients. Methods: Patients with facial skin cancer who underwent surgery were enrolled at 4 hospitals across the United States. A total of 990 patients were included. The FACE-Q Skin Cancer questionnaire was administered before surgery, at 2-week, 6-month, and 1-year intervals postsurgery. Results: Patients reported increased satisfaction with FACE-Q scales over 1 year. Significant factors influencing outcomes included sex, age, history of facial skin cancer, cosmetic surgery, defect size, and cancer location. Males reported higher satisfaction with appearance (P = .003) and scar (P < .001), and reduced psychosocial distress (P < .001). Larger defects were associated with greater psychosocial distress (P = .037) and lower scar appraisal (P = .008). Patients with nose skin cancer reported lower satisfaction with appearance and scars (P = .026, P < .001), higher psychosocial distress (P = .004), and increased cancer worry (P = .045). Patients with cancer near the eyes reported increased cancer worry (P = .004). Reconstruction types did not influence satisfaction. Conclusions: Clinical and patient characteristics significantly influence patient-reported outcomes, highlighting the need for personalized treatment approaches to optimize outcomes in dermatologic surgery. © 2025 American Academy of Dermatology, Inc.
Keywords: patient satisfaction; skin cancer; surgery; patient-reported outcomes
Journal Title: Journal of the American Academy of Dermatology
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Publication status: Online ahead of print
Date Published: 2025-03-17
Online Publication Date: 2025-03-17
Language: English
DOI: 10.1016/j.jaad.2025.03.022
PUBMED: 40107508
PROVIDER: scopus
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF. Corresponding MSK author is Erica H. Lee -- Source: Scopus
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MSK Authors
  1. Kishwer S Nehal
    279 Nehal
  2. Stephen Dusza
    289 Dusza
  3. Erica H Lee
    136 Lee
  4. Anthony Rossi
    234 Rossi
  5. Alyce Mei-Shiuan Kuo
    16 Kuo